Concept

In vitro

Related publications (206)

Interference of silver nanoparticles with essential metal homeostasis in a novel enterohepatic fish in vitro system

Silver nanoparticle toxicity has been extensively studied in several vertebrate cells. Its correlation with cellular essential metal homeostasis, however, has largely been overlooked. In this study, we used a novel in vitro model of a fish enterohepatic sy ...

ROYAL SOC CHEMISTRY2019

Non-covalent Methods of Engineering Optical Sensors Based on Single-Walled Carbon Nanotubes

Ardemis Anoush Boghossian, Alice Judith Gillen

Optical sensors based on single-walled carbon nanotubes (SWCNTs) demonstrate tradeoffs that limit their use in in vivo and in vitro environments. Sensor characteristics are primarily governed by the non-covalent wrapping used to suspend the hydrophobic SWC ...

2019

Bioinspired Hydrogels for 3D Organoid Culture

Matthias Lütolf, Delphine Lorraine Perle Blondel

Organoids have stepped into the limelight as unique in vitro systems for modeling organ development, function and disease. This review provides a perspective on how chemically defined, bio-inspired hydrogels could be used for replacing ill-defined matrices ...

SWISS CHEMICAL SOC2019

An ecotoxicological view on neurotoxicity assessment

Wolfgang Schulz

The numbers of potential neurotoxicants in the environment are raising and pose a great risk for humans and the environment. Currently neurotoxicity assessment is mostly performed to predict and prevent harm to human populations. Despite all the efforts in ...

SPRINGEROPEN2018

Calcium phosphate formation on titanium-based surfaces: bioactivity evaluated by in vitro methods

Weitian Zhao

The prediction of implant behaviors in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. In the field of bone implants, it is commonly accepted that a spontaneous formation of a hydroxyapatite (HA) layer on ...

EPFL2018

Peptide-based coatings for flexible implantable neural interfaces

Silvestro Micera

In the last decade, the use of flexible biosensors for neuroprosthetic and translational applications has widely increased. Among them, the polyimide (PI)-based thin-film electrodes got a large popularity. However, the usability of these devices is still h ...

2018

In vivo imaging with microsphere-based super-resolution microscopy

Martinus Gijs, Gergely Huszka, Roger Philippe Krenger

Employing dielectric microspheres in a standard microscope setup is an alternative to image sub-diffraction features optically, however this method suffers from a limited field-of-view. Here, we show our microsphere-based optical super-resolution microscop ...

IEEE2018

Azacyanine dyes and use thereof

Riccardo Sinisi, Alma Rosa Morales Morales

The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are de ...

2018

Explore RdhK based regulatory network of organohalide respiration using a hybrid proteins strategy

Christof Holliger, Julien Maillard, Mathilde Stéphanie Willemin

Reductive dehalogenase (rdh) gene clusters encode for proteins involved in organohalide respiration (OHR), a bacterial process where organohalide compounds are used as terminal electron acceptors. RdhK proteins, members of the CRP/FNR family of transcripti ...

2018

Towards microstructure fingerprinting: Estimation of tissue properties from a dictionary of Monte Carlo diffusion MRI simulations

Jean-Philippe Thiran, Gabriel Girard, Gaëtan Olivier D Rensonnet, Benoît Macq

Many closed-form analytical models have been proposed to relate the diffusion-weighted magnetic resonance imaging (DW-MRI) signal to microstructural features of white matter tissues. These models generally make assumptions about the tissue and the diffusio ...

2018

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