Publications related to RING finger domain

Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity

Paul Joseph Dyson, Laure Menin, Luc Patiny

RAPTA compounds, ([Ru(eta(6)-arene)(PTA)Cl-2], PTA = 1,3,5-triaza-7-phosphaadamantane), have been reported to overcome drug resistance in cisplatin resistant cells. However, the exact mechanism of these complexes is still largely unexplored. In this study, ...

Elsevier2017

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

Vincenzo Sorrentino

Charcot-Marie-Tooth (CMT) disease type 2 is a genetically heterogeneous group of inherited neuropathies characterized by motor and sensory deficits as a result of peripheral axonal degeneration. We recently reported a frameshift (FS) mutation in the Really ...

Oxford Univ Press2017

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

Michaël Imbeault

PRDM9 binding localizes almost all meiotic recombination sites in humans and mice. However, most PRDM9-bound loci do not become recombination hotspots. To explore factors that affect binding and subsequent recombination outcomes, we mapped human PRDM9 bind ...

Elife Sciences Publications Ltd2017

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression

Nayuta Yakushiji

Polycomb group (PcG) proteins play a pivotal role in silencing developmental genes and help to maintain various stem and precursor cells and regulate their differentiation. PcG factors also regulate dynamic and complex regional specification, particularly ...

Company Of Biologists Ltd2016

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking

Georgios Sflomos

Smad anchor for receptor activation (SARA) is highly enriched on endocytic membranes via binding to phosphatidylinositol 3-phosphates through its FYVE (Fab1p-YOTB-Vps27p-EEA1) domain. SARA was originally identified as a protein that recruits non-phosphoryl ...

Nature Publishing Group2013

In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy

Josefina Adriana Maria Bastiaansen

Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...

EPFL2013

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase - The Guardian Angel of DNA

Paul Joseph Dyson, Yury Tsybin, Angela Casini, Alexey Nazarov, Michael Groessl, Gianni Sava

The inhibition activity of a series of anticancer metal complexes based on platinum, ruthenium, and gold metal ions was evaluated on the zinc-finger protein PARP-1, either purified or directly on protein extracts from human breast cancer MCF7 cells. Inform ...

American Chemical Society2011

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

The anthrax toxin is composed of three independent polypeptide chains. Successful intoxication only occurs when heptamerization of the receptor-binding polypeptide, the protective antigen (PA), allows binding of the two enzymatic subunits before endocytosi ...

2006

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

RING finger domain

A chemical biology approach to decipher chromatin ubiquitylation by RNF168

KRAB zinc-finger proteins and their transposable element targets: between antagonism and cooperation

Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking

In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase - The Guardian Angel of DNA

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

Graph Chatbot

Chat with Graph Search

Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity

A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy

LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase - The Guardian Angel of DNA