Concept

Acanthostega

Related publications (4)

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

The tetrapod vertebral column has become increasingly complex during evolution as an adaptation to a terrestrial life. At the same time, the evolution of the vertebral formula became subject to developmental constraints acting on the size of the cervical a ...

Elsevier2015

From lamprey to salamander: an exploratory modeling study on the architecture of the spinal locomotor networks in the salamander

Auke Ijspeert, Andrej Bicanski

The evolutionary transition from water to land required new locomotor modes and corresponding adjustments of the spinal "central pattern generators" for locomotion. Salamanders resemble the first terrestrial tetrapods and represent a key animal for the stu ...

Springer Berlin Heidelberg2013

Function of the Evx-2 gene in the morphogenesis of vertebrate limbs

Denis Duboule

Vertebrate gene members of the HoxD complex are essential for proper development of the appendicular skeletons. Inactivation of these genes induces severe alterations in the size and number of bony elements. Evx-2, a gene related to the Drosophila even-ski ...

1996

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

Denis Duboule

Vertebrate Hoxd genes are sequentially activated during the morphogenesis and pattern formation of the limb. Using the approach of gene disruption via homologous recombination in embryonic stem cells, we have assessed the function of the last gene of the c ...

1993

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