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Background: Coronary artery disease (CAD) is in part genetically determined. Aging is accentuated in people with human immunodeficiency virus (HIV) (PLWH). It is unknown whether genetic CAD event prediction in PLWH is improved by applying individual polyge ...
This book concerns the regulation of transport within a European context, covering air, inland waterways, rail, road passenger and freight, urban public transport, and short sea shipping. All these sectors have experienced substantial changes over the past ...
A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression ...
American Association for the Advancement of Science2013
The handbook aims at raising awareness on the challenge of extending TOD to RUR, the social and environmental challenges, and offers planners, NGOs and interest groups hands-on methods and approaches to understand and analyse local land- scape values of st ...
Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is the leading cause of cirrhosis in North America. Although the recommended treatment for chronic infection involves a 48-week course of peginterferon-alpha-2b (PegIFN ...
Evolution can be described as the change of allele frequencies over time. Four forces - mutation, migration, genetic drift, and selection, drive this change. The aim of my thesis was to accurately estimate and differentiate the parameters governing each of ...
This research study offers a reflection on the Alpine urban condition through the observation of the spaces of production. Departing from the premise that the tourist economy cannot be the only possible horizon for Alpine development, this thesis reflects ...
Europe is perceived to be lagging behind the US in converting its academic results into economic outcomes. Using new survey data on European and US technology transfer offices (TTOs), we find that differences in academic research, TTO staff and experience ...
Human APOBEC3 cytidine deaminases are intrinsic resistance factors to HIV-1. However, HIV-1 encodes a viral infectivity factor (Vif) that degrades APOBEC3 proteins. In vitro APO-BEC3F (A3F) anti-HIV-1 activity is weaker than A3G but is partially resistant ...
With the advent of next-generation sequencing technologies, large data sets of several thousand loci from multiple conspecific individuals are available. Such data sets should make it possible to obtain accurate estimates of population genetic parameters, ...
