Concept
Philosophy of biology
Related publications (6)
A subcellular biochemical model for T6SS dynamics reveals winning competitive strategies
The type VI secretion system (T6SS) is a broadly distributed interbacterial weapon that can be used to eliminate competing bacterial populations. Although unarmed target populations are typically used to study T6SS function in vitro, bacteria most likely e ...
OXFORD UNIV PRESS2023SPAHM: the spectrum of approximated Hamiltonian matrices representations
Ksenia Briling, Alberto Fabrizio
Physics-inspired molecular representations are the cornerstone of similarity-based learning applied to solve chemical problems. Despite their conceptual and mathematical diversity, this class of descriptors shares a common underlying philosophy: they all r ...
2022Multi-omics reveals abundant mitochondrial genomic and circadian expression variation in the Drosophila Genetic Reference Panel
Modern biology rapidly generates a wealth of data,which can only be analysed computationally.Despite the variety of available data types,most of them aim to provide an answer to one question: how does genotypic diversity translates into phenotypes? This qu ...
EPFL2020Common and unique strategies of male killing evolved in two distinct Drosophila symbionts
Bruno Lemaitre, Toshiyuki Harumoto
Male killing is a selfish reproductive manipulation caused by symbiotic bacteria, where male offspring of infected hosts are selectively killed. The underlying mechanisms and the process of their evolution are of great interest not only in terms of fundame ...
2018Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches
Malaria puts at risk of infection half of the world population and still kills around half a million people every year. The rapid and worrisome rise of drug-resistant malaria parasites hinders the treatment of malaria and calls for a global collaboration t ...
EPFL2018Microfluidic front-end technologies for protein electrospray mass spectrometry
In the present work, a polymer microfabricated microsprayer is characterised and tested for the mass spectrometric analysis of biomolecules, in particular in the context of protein mass spectrometry and proteomics. As the core of this work deals with analy ...
EPFL2006