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Nucleosome depletion at transcription start sites (TSS) has been documented genome-wide in multiple eukaryotic organisms. However, the mechanisms that mediate this nucleosome depletion and its functional impact on transcription remain largely unknown. We h ...
For simulations of large spiking neuron networks, an accurate, simple and versatile single-neuron modeling framework is required. Here we explore the versatility of a simple two-equation model: the adaptive exponential integrate-and-fire neuron. We show th ...
The role of biofilms in the pathogenesis of mycobacterial diseases remains largely unknown. Mycobacterium ulcerans, the etiological agent of Buruli ulcer, a disfiguring disease in humans, adopts a biofilm-like structure in vitro and in vivo, displaying an ...
JPEG XR is the newest image coding standard from the JPEG committee. It primarily targets the representation of continuous-tone still images such as photographic images, and achieves high image quality, on par with JPEG 2000, while requiring low computatio ...
Compressed sensing (CS) deals with the reconstruction of sparse signals from a small number of linear measurements. One of the main challenges in CS is to find the support of a sparse signal from a set of noisy observations. In the CS literature, several i ...
Coping with mild early life stress tends to make subsequent coping efforts more effective and therefore more likely to be used as a means of arousal regulation and resilience. Here we show that this developmental learning-like process of stress inoculation ...
A recent study in BMC Evolutionary Biology shows that many of the open reading frames in mammalian Hox genes are more conserved than expected on the basis of their protein sequence. The presence of highly conserved DNA elements is thus not confined to the ...
We presented a series of single lines giving the illusion of a single element moving across the screen. The lines were composed of two vertical segments separated by a small gap. One of the lines was offset, that is the lower segment was not aligned with t ...
Locomotor training improves function after a spinal cord injury both in experimental and clinical settings. The activity-dependent mechanisms underlying such improvement, however, are sparsely understood. Adult rats received a complete spinal cord transect ...
This paper addresses the problem of correct recovery of multiple sparse correlated signals using distributed thresholding. We consider the scenario where multiple sensors capture the same event, but observe different signals that are correlated by local tr ...