United States v. E. C. Knight Co., 156 U.S. 1 (1895), also known as the "Sugar Trust Case," was a United States Supreme Court antitrust case that severely limited the federal government's power to pursue antitrust actions under the Sherman Antitrust Act. In Chief Justice Melville Fuller's majority opinion, the Court held that the US Congress could not regulate manufacturing and thus gave state governments the sole power to take legal action against manufacturing monopolies. The case has never been overruled, but in Swift & Co. v. United States and subsequent cases, the Court has held that Congress can regulate manufacturing when it affects interstate commerce.
In 1892, the American Sugar Refining Company gained control of the E. C. Knight Company and several others, which resulted in a 98% monopoly of the American sugar refining industry. US President Grover Cleveland, in his second term of office (1893–1897), directed the national government to sue the Knight