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Glut-2 is a low-affinity transporter present in the plasma membrane of pancreatic beta-cells, hepatocytes and intestine and kidney absorptive epithelial cells of mice. In beta-cells, Glut-2 has been proposed to be active in the control of glucose-stimulate ...
Enantiomeric oligoribonucleotides (ent-RNA) up to a sequence length of 35, consisting of the (L-configurated) nucleosides ent-adenosine, ent-guanosine, ent-cytidine, ent-uridine, and 1-(b-L-ribofuranosyl)thymine were prepd. by automated synthesis from appr ...
A miniaturised Total chemical Analysis System (μTAS) for glucose and lactate measurement in biological samples constructed based on an integrated microdialysis sampling and detection system. The complete system incorporates a microdialysis probe for intrav ...
A tight coupling exists between neuronal activity and energy metabolism. Over a century ago Roy and Sherrington postulated that “the brain possesses intrinsic mechanisms by which its vascular supply can be varied locally in correspondence with local variat ...
Understanding the mechanism of brain glucose transport across the blood- brain barrier is of importance to understanding brain energy metabolism. The specific kinetics of glucose transport nave been generally described using standard Michaelis-Menten kinet ...
Continuous cultures of a hybridoma cell line (Zac3) were performed in a stirred tank reactor with protein-free media. At steady state the medium was replaced by one contg. U-14C-labeled glucose. The fluxes leaving the reactor were analyzed with a scintilla ...
A series of novel, surface-active, inorganometallic complexes of osmium were synthesized and then characterized (using electrochemical techniques) as electron transfer mediators for glucose oxidase (EC 1.1.3.4, GOD) from Aspergillus niger. The mediators co ...
The objective of this study was to characterize the dynamic adaptation of the oxidative capacity of Saccharomyces cerevisiae to an increase in the glucose supply rate and its implications for the control of a continuous culture designed to produce biomass ...
Using optimized administration of 13C-labeled glucose, the time course of the specific activity of glucose was measured directly by in vivo 13C-NMR in the human brain at 4 Tesla. Subsequent label incorporation was measured at the C2, C3 and C4 positions of ...
Signals detected with functional brain imaging techniques are based on the coupling between neuronal activity and energy metabolism. Positron emission tomography signals detect blood flow, oxygen consumption and glucose utilization associated with neuronal ...
