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This thesis investigates the role of the amygdala for the establishment of fear memories with a multidisciplinary approach, including behavioural, psychopharmacological, genetic, molecular, and electrophysiological techniques in rats or mice, under healthy ...
Tumor necrosis factor (TNF) alpha, interleukins (IL) 2, 4, 6, and 10, and IgG oligoclonal bands (IgG OB) in vitro production was assessed, after whole-blood stimulation with lipopolysaccharide or concanavalin A, in 61 patients presenting with relapsing-rem ...
Epigenetic mechanisms, such as histone modifications, regulate responsiveness to drugs of abuse, such as cocaine, but relatively little is known about the regulation of addictive-like behaviors by DNA methylation. To investigate the influence of DNA methyl ...
Understanding how a frictional interface fails, and how past ruptures will affect the propagation of the following ruptures is fundamental to a better comprehension of earthquake behavior. In that sense, numerical simulations provide a useful tool to study ...
In this contribution we present multi-channel microinjector arrays fabricated by a reliable three-layer SU-8 process for the local delivery of specific substances into brain tissue. They are designed to be assembled with previously developed. implantable b ...
Regimens recommended to treat latent tuberculosis infection (LTBI) are 3 to 9 months long. A 2-month rifampin+pyrazinamide regimen is no longer recommended. Shorter regimens are highly desirable. Because substituting rifapentine for rifampin in the standar ...
Most of the Central Pattern Generator (CPG) models are based on defining explicit dynamical systems and finding the appropriate parameters. In this paper, we propose a novel CPG model that is based on altering a nonlinear oscillator to obtain desired limit ...
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In vitro production of tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (IL-2), IL-4, IL-6, IL-10 and oligoclonal IgG (IgG OB) was evaluated in the aim to investigate their profile in correlation with multiple sclerosis (MS) clinical activity and cli ...
In tuberculosis, it is often important to establish the source of infection and to determine whether disease is due to a new strain of Mycobacterium tuberculosis or to relapse. To cope with the resurgence of tuberculosis and atypical mycobacterioses in AID ...