Concept

Organ transplantation

Related publications (94)

TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

Breast cancer metastasis is a complex process that depends not only on intrinsic characteristics of metastatic stem cells, but also on the particular microenvironment that supports their growth and modulates the plasticity of the system. In search for micr ...

2020

Human genomics of acute liver failure due to hepatitis B virus infection: An exome sequencing study in liver transplant recipients

Jacques Fellay, Christian Hammer, Nimisha Chaturvedi, Petar Scepanovic, Samira Asgari

Acute liver failure (ALF) or fulminant hepatitis is a rare, yet severe outcome of infection with hepatitis B virus (HBV) that carries a high mortality rate. The occurrence of a life-threatening condition upon infection with a prevalent virus in individuals ...

2019

Efficient decellularization of equine tendon with preserved biomechanical properties and cytocompatibility for human tendon surgery indications

Dominique Pioletti, Nathalie Hirt-Burri, Jens Antons, Cédric Peneveyre, Anthony Grognuz, Pierre-Arnaud Aeberhard

Chronic and acute tendon injuries are frequent afflictions, for which treatment is often long and unsatisfactory. When facing extended injuries, matrices and scaffolds with sufficient biomechanical properties are required for surgical repair and could addi ...

2019

Ensuring robust and tissue-independent operation of implantable, ingestible, and injectable antennas

Denys Nikolayev

In-body bioelectronics relies on antennas to interface with external on- or off-body equipment. In this paper, we address the impedance detuning of in-body antennas caused by nondeterministic electromagnetic properties of biological tissues. The impedance ...

IEEE2019

Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor

Hatice Altug, Alexander Belushkin

y Sepsis is a condition characterized by a severe stage of blood-infection often leading to tissue damage, organ failure and finally death. Fast diagnosis and identification of the sepsis stage (sepsis, severe sepsis or septic shock) is critical for the pa ...

ELSEVIER SCIENCE BV2019

Bioinspired Hydrogels for 3D Organoid Culture

Matthias Lütolf, Delphine Lorraine Perle Blondel

Organoids have stepped into the limelight as unique in vitro systems for modeling organ development, function and disease. This review provides a perspective on how chemically defined, bio-inspired hydrogels could be used for replacing ill-defined matrices ...

SWISS CHEMICAL SOC2019

Tissue-Engineering the Intestine: The Trials before the Trials

Matthias Lütolf

Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment ...

CELL PRESS2019

Automatically Starting and Secured Detent Escapement for a Timepiece

Simon Nessim Henein, Ilan Vardi

A horological detent escapement for a horological movement arranged to transmit a torque from said horological movement to an oscillating regulating organ of said horological movement, the regulating organ comprising a first mobile body and the escapement ...

2019

Anti-fibrotic effect of ketoprofen-grafted alginate microcapsules in the transplantation of insulin producing cells

Sandrine Gerber, François Rémi Pierre Noverraz, Daniel Ortiz Trujillo, Luca Szabó, Léo Bühler

The controlled release of small molecular modulators of the immune response from hydrogel microspheres (MS) used for cell immobilization is an attractive approach to reduce pericapsular fibrotic overgrowth (PFO) after transplantation. Ketoprofen is a well- ...

2018

Consensus guidelines for the use and interpretation of angiogenesis assays

Michele De Palma, George Coukos, Patrycja Nowak-Sliwinska, Elizabeth Anne Allen, Yan Gong

The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that ...

2018

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