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We investigated the impact of thalamus on ongoing cortical activity in the awake, behaving mouse. We demonstrate that the desynchronized cortical state during active behavior is driven by a centrally generated increase in thalamic action potential firing, ...
Environmental light synchronizes the primary mammalian biological clock in the suprachiasmatic nuclei, as well as many peripheral clocks in tissues and cells, to the solar 24-hour day. Light is the strongest synchronizing agent (zeitgeber) for the circadia ...
Under normal viewing conditions, due to the motion of objects and to eye movements, the retinotopic representation of the environment constantly changes. Yet we perceive the world as stable, and we easily keep track of moving objects. Here, we investigated ...
Association for Research in Vision and Ophthalmology2012
The spatial representation of a visual scene in the early visual system is well known. The optics of the eye map the three-dimensional environment onto two-dimensional images on the retina. These retinotopic representations are preserved in the early visua ...
Under normal viewing conditions, due to the motion of objects and to eye movements, the retinotopic representation of the environment constantly changes. Yet we perceive the world as stable, and we easily keep track of moving objects. Here, we investigated ...
Discomfort glare, among different aspects of visual discomfort is a phenomenon which is little understood and hard to quantify. As this phenomenon is dependent on the building occupant’s view direction and on the relative position of the glare source, a de ...
Ageing is associated with marked changes in sleep timing, structure and electroencephalographic (EEG) activity. Older people exhibit less slow-wave and spindle activity during non-rapid eye movement (NREM) sleep, together with attenuated levels of rapid ey ...
DAYLIGHT is a desirable architectural component that satisfies both visual and psychological needs of the occupants. Therefore it is essential to integrate this component in the design in a way that maximum daylight is guaranteed and a visually healthy and ...
Evening bright light exposure is reported to ameliorate daytime sleepiness and age-related sleep complaints, and also delays the timing of circadian rhythms. We tested whether evening light exposure given to older adults with sleep–wake complaints would de ...
The quality of sleep has recently come to the forefront of public health concerns in industrialized nations. Indeed, voluntary sleep curtailment is widespread, sleep disorders are increasingly recognized and both correlate with the current epidemiology of ...
