Publications related to Chemical biology

Aerolysin, a Powerful Protein Sensor for Fundamental Studies and Development of Upcoming Applications

The nanopore electrical approach is a breakthrough in single molecular level detection of particles as small as ions, and complex as biomolecules. This technique can be used for molecule analysis and characterization as well as for the understanding of con ...

AMER CHEMICAL SOC2019

Non‐Planar and Flexible Hole‐Transporting Materials from Bis‐Xanthene and Bis‐Thioxanthene Units for Perovskite Solar Cells

Mohammad Khaja Nazeeruddin, Iwan Zimmermann, Giulia Grancini

Two new hole‐transporting materials (HTMs), BX‐OMeTAD and BTX‐OMeTAD , based on xanthene and thioxanthene units, respectively, and bearing p ‐methoxydiphenylamine peripheral groups, are presented for their use in perovskite solar cells (PSCs). The novelty ...

2019

A molecular logic gate enables super-resolved imaging of intracellular lipid droplets

Pablo Rivera Fuentes, Adam Miklos Eördögh

Photoactivatable dyes enable single-mol. imaging in biol. Despite progress in the development of new fluorophores and labeling strategies, many cellular compartments remain difficult to image beyond the limit of diffraction in living cells. For example, li ...

2019

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

Thierry Meyer, Jérôme Waser, Stefano Nicolai, Annik Nanchen, Raphaël Michel Henri Simonet-Davin, Sébastien Pierre Louis Alazet, Johannes Preindl

Azides are building blocks of increasing importance in synthetic chemistry, chemical biology, and materials science. Azidobenziodoxolone (ABX, Zhdankin reagent) is a valuable azide source, but its safety profile has not been thoroughly established. Herein, ...

2018

Ethynyl benziodoxolones: functional terminators for cell-penetrating poly(disulfide)s

Jérôme Waser, Stefan Matile, Romain Gaëtan Tessier

Outperforming cell-penetrating peptides (CPPs), cell-penetrating poly(disulfide)s (CPDs) are attracting increasing interest. CPDs are accessible by ring-opening disulfide-exchange polymerization under mild conditions in neutral water. Initiation of the pol ...

Royal Society of Chemistry2016

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Paul Joseph Dyson, Christian Hartinger

The clinical development of anticancer metallodrugs is often hindered by the elusive nature of their molecular targets. To identify the molecular targets of an antimetastatic ruthenium organometallic complex based on 1,3,5-triaza-7-phosphaadamantane (RAPTA ...

2015

Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents

Jérôme Waser, Chao Wang, Reto Frei, Durga Prasada Rao Hari

In this study, we present a highly efficient method for proteomic profiling of cysteine residues in complex proteomes and in living cells. Our method is based on alkynylation of cysteines in complex proteomes using a clickable alkynyl benziodoxolone bearin ...

Wiley-Blackwell2015

Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents

Jérôme Waser, Franck Le Vaillant, Thibaut Christian Courant

Alkynes are used as building blocks in synthetic and medicinal chemistry, chemical biology, and materials science. Therefore, efficient methods for their synthesis are the subject of intensive research. Herein, we report the direct synthesis of alkynes fro ...

Wiley-Blackwell2015

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Chemical biology

Aerolysin, a Powerful Protein Sensor for Fundamental Studies and Development of Upcoming Applications

Non‐Planar and Flexible Hole‐Transporting Materials from Bis‐Xanthene and Bis‐Thioxanthene Units for Perovskite Solar Cells

A molecular logic gate enables super-resolved imaging of intracellular lipid droplets

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

Can Biomimetic Zinc Compounds Assist a (3 + 2) Cycloaddition Reaction? A Theoretical Perspective

Ethynyl benziodoxolones: functional terminators for cell-penetrating poly(disulfide)s

Encoded libraries of chemically modified peptides

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents

Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents

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Chat with Graph Search

Aerolysin, a Powerful Protein Sensor for Fundamental Studies and Development of Upcoming Applications

Non‐Planar and Flexible Hole‐Transporting Materials from Bis‐Xanthene and Bis‐Thioxanthene Units for Perovskite Solar Cells

A molecular logic gate enables super-resolved imaging of intracellular lipid droplets

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

Can Biomimetic Zinc Compounds Assist a (3 + 2) Cycloaddition Reaction? A Theoretical Perspective

Encoded libraries of chemically modified peptides

Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents

Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Ethynyl benziodoxolones: functional terminators for cell-penetrating poly(disulfide)s

Room-Temperature Decarboxylative Alkynylation of Carboxylic Acids Using Photoredox Catalysis and EBX Reagents