Publications related to Tau protein

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Pierre Gönczy, Georgios Hatzopoulos, Paul Guichard

Centrioles are microtubule-based structures that play important roles notably in cell division and cilium biogenesis. CEP135/Bld10p family members are evolutionarily conserved microtubule-binding proteins important for centriole formation. Here, we analyze ...

Elsevier2016

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

Françoise Gisou van der Goot Grunberg

Ubiquitin-specific protease 19 (USP19) is one of the deubiquitinating enzymes (DUBs) involved in regulating the ubiquitination status of substrate proteins. There are two major isoforms of USP19 with distinct C-termini; the USP19_a isoform has a transmembr ...

Public Library of Science2016

Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein

Hilal Lashuel, Klodjan Stafa, Simona Eleuteri

Parkinson's disease (PD) is a common neurodegenerative disorder. Functional interactions between some PD genes, like PINK1 and parkin, have been identified, but whether other ones interact remains elusive. Here we report an unexpected genetic interaction b ...

2015

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

Patrick Aebischer, Bernard Schneider

Alzheimer's disease is the most prevalent tauopathy and cause of dementia. We investigate the hypothesis that reactivation of plasticity can restore function in the presence of neuronal damage resulting from tauopathy. We investigated two models with tau h ...

2015

Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein

Hilal Lashuel, Bruno Claude Daniel Fauvet

Posttranslational modifications (PTMs) serve as molecular switches for regulating protein folding, function, and interactome and have been implicated in the misfolding and amyloid formation by several proteins linked to neurodegenerative diseases, includin ...

2015

The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein

Maurizio Molinari

Although the accumulation of a misfolded and protease-resistant form of the prion protein (PrP) is a key event in prion pathogenesis, the cellular factors involved in its folding and quality control are poorly understood. PrP is a glycosylated and disulfid ...

Amer Soc Biochemistry Molecular Biology Inc2015

Real-time Protein Aggregation Monitoring based on a Simultaneous Light Scattering Investigation and a Bloch Surface Wave-based Approach

Hans Peter Herzig, Elsie Barakat, Sara Santi

We present a study of the dynamics of protein aggregation using a Bloch surface wave (BSW) label-free sensing scheme. In a previous work, we demonstrated the ability to detect the early dynamic events of fibrillogenesis of amyloid beta-peptides (A beta), l ...

Spie-Int Soc Optical Engineering2015

Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Giovanni Dietler, Giovanni Longo, Francesco Simone Ruggeri, Ewelina Wioletta Lipiec

Amyloids are insoluble protein fibrillar aggregates. The importance of characterizing their aggregation has steadily increased because of their link to human diseases and material science applications. In particular, misfolding and aggregation of the Josep ...

Nature Publishing Group2015

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Tau protein

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein

The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein

Ultrafast photoinduced processes in metal - containing molecular complexes and in proteins

Real-time Protein Aggregation Monitoring based on a Simultaneous Light Scattering Investigation and a Bloch Surface Wave-based Approach

Recapitulating De Novo Alpha-Synuclein Fibrillization in a Novel Neuronal Model of Parkinson's Disease

Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Graph Chatbot

Chat with Graph Search

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Recapitulating De Novo Alpha-Synuclein Fibrillization in a Novel Neuronal Model of Parkinson's Disease

Real-time Protein Aggregation Monitoring based on a Simultaneous Light Scattering Investigation and a Bloch Surface Wave-based Approach

Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein

The Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein

Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein

Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Ultrafast photoinduced processes in metal - containing molecular complexes and in proteins