Kary Banks Mullis (December 28, 1944 - August 7, 2019) was an American biochemist. In recognition of his role in the invention of the polymerase chain reaction (PCR) technique, he shared the 1993 Nobel Prize in Chemistry with Michael Smith and was awarded the Japan Prize in the same year. PCR became a central technique in biochemistry and molecular biology, described by The New York Times as "highly original and significant, virtually dividing biology into the two epochs of before PCR and after PCR." Mullis also downplayed humans' role in climate change and expressed doubts that HIV is the sole cause of AIDS. He also expressed a belief in the paranormal, particularly around ghosts. Mullis' work in advocating for topics completely unrelated to his Nobel Prize has been cited as an example of the trend known as the 'Nobel disease'. Mullis was born in Lenoir, North Carolina, near the Blue Ridge Mountains, on December 28, 1944, to Cecil Banks Mullis and Bernice Barker Mullis. His family had a background in farming in this rural area. As a child, Mullis said, he was interested in observing organisms in the countryside. He and his cousins would often taunt livestock by feeding them through electric fences, and Kary was mostly interested in the spiders in his grandparents' basement. He grew up in Columbia, South Carolina, where he attended Dreher High School, graduating in the class of 1962. He recalled his interest in chemistry beginning when he learned how to chemically synthesize and build solid fuel propulsion rockets as a high school student during the 1960s. He earned a Bachelor of Science in chemistry from the Georgia Institute of Technology in Atlanta in 1966, during which time he married his first wife, Richards Haley, and started a business. He earned his PhD in 1973 in biochemistry at the University of California, Berkeley (UC Berkeley), in J. B. Neilands' laboratory, which focused on synthesis and structure of bacterial iron transporter molecules.