Concept

Diathesis–stress model

Related publications (104)

Simultaneous initiation and growth of multiple radial hydraulic fractures from a horizontal wellbore

Multi-stage fracturing is the current preferred method of completion of horizontal wells in unconventional hydrocarbon reservoirs. Its core component consists in simultaneously initiating and propagating an array of hydraulic fractures. We develop a numeri ...

Pergamon-Elsevier Science Ltd2015

Determination of minimum CFRP pre-stress levels for fatigue crack prevention in retrofitted metallic beams

Alain Nussbaumer, Gary Scott Prinz, Andrin Herwig, Elyas Ghafoori

The majority of fatigue strengthening studies focus on reducing propagation rates of existing cracks, ignoring the crack initiation stage. Many existing metallic bridge members however do not contain existing cracks, but rather are nearing their design fat ...

Elsevier2015

Design criterion for fatigue strengthening of riveted beams in a 120-year-old railway metallic bridge using pre-stressed CFRP plates

Alain Nussbaumer, Gary Scott Prinz, Andrin Herwig, Elyas Ghafoori

This study presents a design criterion developed for fatigue strengthening of a 120-year-old metallic railway bridge in Switzerland and presents a pre-stressed un-bonded reinforcement (PUR) system developed to apply the strengthening. The PUR system uses c ...

Elsevier2015

Effect on Bridge Load Effects of Vehicle Transverse In-Lane Position: A Case Study

Mark Anthony Treacy

This paper presents an investigation of the influence of vehicle transverse in-lane position on bridge traffic load effects. To analyze the influence, both finite-element analysis and statistical analysis methods are used, and various technical aspects are ...

American Society of Civil Engineers2015

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Michael van der Kooij, Martina Fantin, Céline Fournier

Chronic stress is a risk factor for the development of psychopathologies characterized by cognitive dysfunction and deregulated social behaviours. Emerging evidence suggests a role for cell adhesion molecules, including nectin-3, in the mechanisms that un ...

2014

Stratified medicine for mental disorders

Maria del Carmen Sandi Perez

There is recognition that biomedical research into the causes of mental disorders and their treatment needs to adopt new approaches to research. Novel biomedical techniques have advanced our understanding of how the brain develops and is shaped by behaviou ...

Elsevier Science Bv2014

CRHR1 links peripuberty stress with deficits in social and stress-coping behaviors

Maria del Carmen Sandi Perez, Orbicia Riccio Wicht, Vandana Veenit

Stressful life events during childhood and adolescence are important risk factors for the development of psychopathologies later in life. The corticotropin releasing hormone (CRH) and the CRH receptor 1 (CRHR1) have been implicated in the link between earl ...

Pergamon-Elsevier Science Ltd2014

Dynamic Brazilian Tests of Granite Under Coupled Static and Dynamic Loads

Yang Zou, Xing Li, Gang Li

Rocks in underground projects at great depth, which are under high static stresses, may be subjected to dynamic disturbance at the same time. In our previous work (Li et al. Int J Rock Mech Min Sci 45(5):739–748, 2008), the dynamic compressive behaviour of ...

Springer Verlag2014

Modelling of fatigue behaviour of bridge deck slab elements strengthened with reinforced UHPFRC

Tohru Makita

With the occurrence of higher and more frequent axle loads on roads, in particular bridge deck slabs are more severely solicitated by fatigue loading. To avoid heavy interventions for strengthening of deck slabs, an improved building material is used, name ...

Crc Press-Taylor & Francis Group2014

Stress–strain analysis of a toric pipe for inner pressure loads

Anton Schleiss, David Ferràs Segura

This research aims to enhance the knowledge on stress–strain states of a coiled pipe used for Hydraulic transient experiments. The membrane theory of shells of revolution has been applied for the description of axial and circumferential strains while an in ...

Elsevier2014

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