Concept
Hydrocyanation
Related publications (49)
Photocatalyzed [2σ + 2σ] and [2σ + 2π] Cycloadditions for the Synthesis of Bicyclo[3.1.1]heptanes and 5- or 6-Membered Carbocycles
Jérôme Waser, Matthew Wodrich, André Bossonnet
We report the use of photocatalysis for the homolytic ring-opening of carbonyl cyclopropanes. In contrast to previous studies, our approach does not require a metal cocatalyst or a strong reductant. The carbonyl cyclopropanes can be employed for both [2σ + ...
2023Nitriles as main products from the oxidation of primary amines by ferrate (VI): Kinetics, mechanisms and toxicological implications for nitrogenous disinfection byproduct control
Woongbae Lee, Yun Ho Lee, Jaedon Shin
Ferrate (Fe(VI)), a promising water treatment oxidant, can be used for micropollutant abatement or disinfection byproduct mitigation. However, knowledge gaps remain concerning the interaction between Fe(VI) and dissolved organic matter structures, notably ...
PERGAMON-ELSEVIER SCIENCE LTD2022Enantio- and diastereoselective construction of vicinal C(sp(3)) centres via nickel-catalysed hydroalkylation of alkenes
Xile Hu, Chao Fan, Srikrishna Bera
In drug discovery, the proportion of aliphatic carbons (C(sp(3))) and the presence of chiral carbons in organic molecules are positively correlated to their chance of clinical success. Although methods exist for the synthesis of chiral C(sp(3))-rich molecu ...
NATURE PORTFOLIO2022Novel cationic 1,2,4-selenadiazoles: synthesis via addition of 2-pyridylselenyl halides to unactivated nitriles, structures and four-center SeMIDLINE HORIZONTAL ELLIPSISN contacts
Euro Solari, Alexander Tskhovrebov
2-Pyridylselenyl halides undergo facile coupling with a triple CN bond of unactivated nitriles. Unprecedented heterocyclization allowed the preparation of a novel class of cationic 1,2,4-selenadiazoles in remarkably high yields. Cationic 1,2,4-selenadiazol ...
ROYAL SOC CHEMISTRY2021Intermolecular oxidative amination of unactivated alkenes by dual photoredox and copper catalysis
Oxidative amination of alkenes via amidyl radical addition is potentially an efficient method to generate allylic amines, which are versatile synthetic intermediates to bioactive compounds and organic materials. Here by combining photochemical generation o ...
ROYAL SOC CHEMISTRY2021Developing the Catalytic Applications of 1,3,2-Diazaphospholenes
The development of new catalytic methods for organic synthesis is a critical endeavour in order to obviate the economic and ecological drawbacks of stoichiometric organic synthesis. While catalysis can offer significant advantages in terms of atom-economy, ...
EPFL2021Propelling the hydrogen economy: from chemical storage and delivery to utilization in biomass conversion
Since H2 is a non-polluting, inexhaustible, efficient, and sustainable energy carrier, it has been forecast to become one of the major carriers of energy in the future and is also essential in the production of feedstock chemicals derived from renewable ca ...
EPFL2021Operando diffuse reflectance infrared detection of cyanide intermediate species during the reaction of formaldehyde with ammonia over V2O(5)/ WO3-TiO2
Davide Ferri, Oliver Kröcher, Rob Jeremiah G. Nuguid
Hydrogen cyanide (HCN) is a highly poisonous gas that can form through the reaction between formaldehyde and ammonia (NH3) in the exhaust. While this detrimental side reaction has been the subject of recent catalytic studies under selective catalytic reduc ...
ELSEVIER2021Copper-Catalyzed Cyanoalkylative Aziridination of N-Sulfonyl Allylamines
Qian Wang, Jieping Zhu, Minh Tu Ha, Weisi Guo
Reaction of N-arylsulfonyl allylamines with alkyl nitriles in the presence of di-tert-butyl peroxide (DTBP) and a catalytic amount of copper salt afforded homologated aziridines in 43-86% yield. A sequence involving addition of the in situ generated cyanom ...
WILEY-V C H VERLAG GMBH2020Palladium-Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3-Disubstituted Indoles
Qian Wang, Jieping Zhu, Hua Wu, Yuping He
We report herein the first examples of a palladiumcatalyzed enantioselective Cacchi reaction for the synthesis of indoles bearing a chiral C2-aryl axis. In the presence of a catalytic amount of Pd(OAc)2 and (R,R)-QuinoxP* ligand, reaction of N-aryl(alkyl)s ...
2020