Concept

Cell junction

Related publications (217)

Synthetic biomaterials as cell-responsive artificial extracellular matrices

Cells in our tissues are exposed to complex arrays of biochemical and biophysical cues from their protein- and sugar-rich extracellular matrix (ECM). In concert with cell- intrinsic regulatory cascades, these temporally and spatially coordinated signals in ...

Imperial College Press2008

Inferring connection proximity in networks of electrically coupled cells by subthreshold frequency response analysis

Henry Markram, Thomas Berger, Michele Giugliano, Corrado Cali, Michele Pignatelli

Electrical synapses continuously transfer signals bi-directionally from one cell to another, directly or indirectly via intermediate cells. Electrical synapses are common in many brain structures such as the inferior olive, the subcoeruleus nucleus and the ...

Springer US2008

Dielectrophoretic sorting on a microfabricated flow cytometer: Label free separation of Babesia bovis infected erythrocytes

Philippe Renaud, Thomas Michael Braschler, Nicolas Demierre

Dielectrophoresis is a method that has demonstrated great potential in cell discrimination and isolation. In this study, the dielectrophoretic sorting of normal and Babesia bovis infected erythrocytes was performed using a microfabricated flow cytometer. S ...

2008

Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds

Andrzej Kulik, Jean-Jacques Meister, Boris Hinz, Kyumin Lee, Philippe Pittet

We have previously shown that the switch from N-cadherin to OB-cadherin expression increases intercellular adhesion between fibroblasts during their transition from a migratory to a fibrogenic phenotype. Using atomic force microscopy we here show that part ...

2008

AMPA receptor imaging by infrared scanning near-field optical microscopy

Giorgio Margaritondo, Kai Johnsson, Harald Hirling, Johanna Generosi, Michel Kropf

Infrared scanning near-field optical microscopy is used to detect AMPA-type glutamate receptor clusters in hippocampal neuron cells. AMPA's GluR2-subunits were marked with the fluorophore Alexa488 and high-resolution micrographs were taken at 6.25 µm wavel ...

2008

Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles

Bruno Lemaitre

Erwinia carotovora are phytopathogenic Gram-negative bacteria of agronomic interest as these bacteria are responsible for fruit soft rot and use insects as dissemination vectors. The Erwinia carotovora carotovora strain 15 (Ecc15) is capable of persisting ...

2008

Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs

Matthias Lütolf, Jeffrey Alan Hubbell

The elucidation of molecular cell-extracellular matrix (ECM) interactions regulating tissue dynamics necessitates straightforward model systems that can dissect the associated physiological complexity into a smaller number of distinct interactions. Here we ...

2007

Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering

Matthias Lütolf, Jeffrey Alan Hubbell, Martin Ehrbar

The molecular engineering of cell-instructive artificial extracellular matrices is a powerful means to control cell behavior and enable complex processes of tissue formation and regeneration. This work reports on a novel method to produce such smart biomat ...

2007

Real Time Analyses of Myogenesis in Behaving Myoblasts

Loïc Jacot-Descombes

Effective Tissue engineering ultimately depends on understanding the interplay between the proliferation and differentiation stages of development. One of the best systems to examine these processes is myogenesis. Activated myoblasts first undergo many rou ...

2007

Real Time Analysis of Myogenesis in Behaving Myoblasts

Loïc Jacot-Descombes

2007

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