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Bisphenol A (BPA) aggregates on Ag(111) shows a polymorphism between two supramolecular motifs leading to formation of distinct networks depending on thermal energy. With rising temperature a dimeric pairing scheme reversibly converts into a trimeric motif ...
The design of multitarget-directed ligands is a promising strategy for discovering innovative drugs. Here, we report a mechanistic study that clarifies key aspects of the dual inhibition of the fatty acid amide hydrolase (FAAH) and the cyclooxygenase (COX) ...
Une évaluation du potentiel de turbinage sur les systèmes d’eaux usées en Suisse a été réalisée au Laboratoire de Constructions Hydrauliques (LCH) en collaboration avec le bureau e-dric.ch. Le potentiel hydroélectrique de chaque STEP a été calculé et compl ...
Within land vertebrate species, snakes display extreme variations in their body plan, characterized by the absence of limbs and an elongated morphology. Such a particular interpretation of the basic vertebrate body architecture has often been associated wi ...
The large-dimension housing complexes in Rome have grown since the late ‘60s as a result of the 1st PEEP planning of 1964. The plan tried to face the large housing emergency caused by the rising urbanization (Albano, 2001). The peripheral areas of the city ...
The need for interfacing structural biology and biophysics to molecular evolution is being increasingly recognized. One part of the big problem is to understand how physics and chemistry shape the sequence space available to functional proteins, while sati ...
Circadian rhythms are oscillations in behavior, metabolism and physiology that have a period close to 24 h. These rhythms are controlled by an internal pacemaker that evolved under strong selective pressures imposed by environmental cyclical changes, mainl ...
Neuraminidase (NA) inhibitors are used for the prevention and treatment of influenza A virus infections. Two subtypes of NA, N1 and N2, predominate in viruses that infect humans, but differential patterns of drug resistance have emerged in each subtype des ...
L'évolution de l'agriculture, à partir des années 50, a généré la désaffectation de nombreux ruraux devenus obsolètes par leur taille. Dans un paysage où chaque construction a un impact considérable et dans une période durant laquelle le manque d'espace po ...
