Publications related to Operon

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

Giovanni Dietler, Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak, Aleksandre Japaridze, Robert Sebastian Kwapich

DNA in bacterial chromosomes and bacterial plasmids is supercoiled. DNA supercoiling is essential for DNA replication and gene regulation. However, the density of supercoiling in vivo is circa twice smaller than in deproteinized DNA molecules isolated from ...

Oxford University Press2015

Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

Johan Auwerx, Norman Lionel Moullan, Nouria Hernandez, Gilles Willemin, Rajat Singh

MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. H ...

Cold Spring Harbor Lab Press, Publications Dept2015

Structure of silent transcription intervals and noise characteristics of mammalian genes

Felix Naef, Benjamin Zoller, Damien Lionel Nicolas

Mammalian transcription occurs stochastically in short bursts interspersed by silent intervals showing a refractory period. However, the underlying processes and consequences on fluctuations in gene products are poorly understood. Here, we use single allel ...

Nature / European Molecular Biology Organization2015

Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations

Andrew Charles Oates, Daniele Soroldoni

We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence of cooperative binding, and consider different hypotheses for how the numbe ...

2014

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23

Christof Holliger, Julien Maillard, Yue Lu, Aamani Rupakula Boyanapalli, Hauke Smidt

Introduction: Corrinoids are an essential cofactor of reductive dehalogenases, the key enzymes of organohalide respiration (OHR). Dehalobacter restrictus strain PER-K23 is an obligate OHR bacterium able to conserve energy with tetrachloroethene, but is una ...

2014

Johan Auwerx

The estrogen-related receptor- (ERR) regulates mitochondrial biogenesis and glucose and fatty acid oxidation during differentiation in skeletal myocytes. However, whether ERR controls metabolic remodeling during skeletal muscle regeneration in vivo is unkn ...

Federation of American Society of Experimental Biology2014

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

Camille Véronique Bernadette Goemans

We report a new function for Escherichia coli DsbC, a protein best known for disulfide bond isomerization in the periplasm. We found that DsbC regulates the redox state of the single cysteine of the l-arabinose-binding protein AraF. This cysteine, which ca ...

2014

Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

Bart Deplancke, David Hacker, Sebastian Martin Waszak, Sunil Kumar Raghav, Nouria Hernandez, Gilles Udin, Alisa Yurovsky, Julien Bryois, Sarah Thurnheer

DNA sequence variation has been associated with quantitative changes in molecular phenotypes such as gene expression, but its impact on chromatin states is poorly characterized. To understand the interplay between chromatin and genetic control of gene regu ...

American Association for the Advancement of Science2013

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Operon

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

Structure of silent transcription intervals and noise characteristics of mammalian genes

Predicting the genes regulated by microRNAs via binding sites in the 3' untranslated and coding regions

Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23

Estrogen-related receptor-alpha ( ERR alpha) deficiency in skeletal muscle impairs regeneration in response to injury

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

Multiscale Spatial Organization of RNA Polymerase in Escherichia coli

Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

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Chat with Graph Search

Structure of silent transcription intervals and noise characteristics of mammalian genes

Predicting the genes regulated by microRNAs via binding sites in the 3' untranslated and coding regions

Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations

Estrogen-related receptor-alpha ( ERR alpha) deficiency in skeletal muscle impairs regeneration in response to injury

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

Corrinoid Auxotrophy in the Obligate Organohalide-Respiring Dehalobacter restrictus strain PER-K23

Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

Multiscale Spatial Organization of RNA Polymerase in Escherichia coli