Publications related to ATP synthase

N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate. In the brain, NAA is considered an important energy metabolite for lipid synthesis. However, the role of NAA in peripheral tissues r ...

FEDERATION AMER SOC EXP BIOL2019

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Henning Paul-Julius Stahlberg

ABC toxins are pore-forming virulence factors produced by pathogenic bacteria. YenTcA is the pore-forming and membrane binding A subunit of the ABC toxin YenTc, produced by the insect pathogen Yersinia entomophaga. Here we present cryo-EM structures of Yen ...

Springer Science and Business Media LLC2019

Structure of the mitochondrial import gate reveals distinct preprotein paths

Marilena Wischnewski, Jian Qiu, Thomas Becker

The translocase of the outer mitochondrial membrane (TOM) is the main entry gate for proteins(1-4). Here we use cryo-electron microscopy to report the structure of the yeast TOM core complex(5-9) at 3.8-angstrom resolution. The structure reveals the high-r ...

2019

The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

Melanie Blokesch, Sandrine Stutzmann, Candice Stoudmann, David William Adams, Jorge André Matias Pereira

Type IV pili are dynamic cell surface appendages found throughout the bacteria. The ability of these structures to undergo repetitive cycles of extension and retraction underpins their crucial roles in adhesion, motility and natural competence for transfor ...

2019

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Henning Paul-Julius Stahlberg

ABCG2 is a transporter protein of the ATP-binding-cassette (ABC) family that is expressed in the plasma membrane in cells of various tissues and tissue barriers, including the blood-brain, blood-testis and maternal-fetal barriers(1-4). Powered by ATP, it t ...

Springer Nature America, Inc2018

Structure of a PSI-LHCI-cyt b(6)f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions

Henning Paul-Julius Stahlberg

Photosynthetic linear electron flow (LEF) produces ATP and NADPH, while cyclic electron flow (CEF) exclusively drives photophosphorylation to supply extra ATP. The fine-tuning of linear and cyclic electron transport levels allows photosynthetic organisms t ...

Proceedings of the National Academy of Sciences2018

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population

Johan Auwerx, Jun Yong Kim, Dongryeol Ryu, Evan Graehl Williams, Pooja Jha, Jiayi Lan, Ruedi Aebersold, Moaraj Hasan

We have used SWATH mass spectrometry to quantify 3648 proteins across 76 proteomes collected from genetically diverse BXD mouse strains in two fractions (mitochondria and total cell) from five tissues: liver, quadriceps, heart, brain, and brown adipose (BA ...

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC2018

Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Paolo De Los Rios, Alessandro Barducci, Pierre Goloubinoff, Bruno Claude Daniel Fauvet, Alberto Stefano Sassi

During and after protein translation, molecular chaperones require ATP hydrolysis to favor the native folding of their substrates and, under stress, to avoid aggregation and revert misfolding. Why do some chaperones need ATP, and what are the consequences ...

2018

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ATP synthase

N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

Mechanistic insights into AMP-activated protein kinase-dependent gene expression

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Structure of the mitochondrial import gate reveals distinct preprotein paths

The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Structure of a PSI-LHCI-cyt b(6)f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population

Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Novel tools to dissect stem cell metabolism at single cell level

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Chat with Graph Search

Mechanistic insights into AMP-activated protein kinase-dependent gene expression

Structure of a PSI-LHCI-cyt b(6)f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions

Novel tools to dissect stem cell metabolism at single cell level

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins

Structure of the mitochondrial import gate reveals distinct preprotein paths

The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population