ScopolamineScopolamine, also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin after about 20 minutes and last for up to 8 hours. It may also be used orally and as a transdermal patch since it has been long known to have transdermal bioavailability.
Psychoactive drugA psychoactive drug, psychopharmaceutical, psychoactive agent, or psychotropic drug is a chemical substance that changes the function of the nervous system and results in alterations of perception, mood, cognition, and behavior. These substances may be used medically, recreationally, for spiritual reasons (for example, by altering one's consciousness, as with entheogens for ritual, spiritual, or shamanic purposes), or for research. Some categories of psychoactive drugs may be prescribed by physicians and other healthcare practitioners because of their therapeutic value.
MuscimolMuscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom. Muscimol is a potent and selective orthosteric agonist for the GABAA receptors and displays sedative-hypnotic, depressant and hallucinogenic psychoactivity. This colorless or white solid is classified as an isoxazole. Muscimol went under clinical trial phase I for epilepsy, but the trial was discontinued. Muscimol is one of the psychoactive compounds responsible for the effects of Amanita muscaria intoxication.
Amanita muscariaAmanita muscaria, commonly known as the fly agaric or fly amanita, is a basidiomycete of the genus Amanita. Native throughout the temperate and boreal regions of the Northern Hemisphere, Amanita muscaria has been unintentionally introduced to many countries in the Southern Hemisphere, generally as a symbiont with pine and birch plantations, and is now a true cosmopolitan species. It associates with various deciduous and coniferous trees.
DoxylamineDoxylamine, sold under the brand name Unisom among others, is an antihistamine medication which is used in the treatment of insomnia and allergies. In combination with pyridoxine (vitamin B6), it is also used to treat morning sickness in pregnant women. Doxylamine is available over-the-counter, and is used in nighttime cold medicines, such as NyQuil, as well as in pain medications containing acetaminophen and codeine, to help with sleep. The medication is taken by mouth.
PsychonauticsPsychonautics (from the Ancient Greek ψυχή psychē 'soul, spirit, mind' and ναύτης naútēs 'sailor, navigator') refers both to a methodology for describing and explaining the subjective effects of altered states of consciousness, including those induced by meditation or mind-altering substances, and to a research cabal in which the researcher voluntarily immerses themselves into an altered mental state in order to explore the accompanying experiences.
Mandragora officinarumMandragora officinarum is the type species of the plant genus Mandragora in the nightshade family Solanaceae. It is often known as mandrake, although this name is also used for other plants. , sources differed significantly in the species they use for Mandragora plants native to the Mediterranean region. The main species found around the Mediterranean is called Mandragora autumnalis, the autumn mandrake. In a broader circumscription, all the plants native to the regions around the Mediterranean Sea are placed in M.
LatuaLatua pubiflora (Griseb.) Baillon, (common name in Spanish: árbol de los brujos, tree of the sorcerers) is the single species of the monotypic genus Latua Phil., endemic to the coastal mountains of southern Chile. A shrub or small tree to 10 m in height, bearing attractive, magenta-to-red, hummingbird-pollinated flowers, it is extremely poisonous – hallucinogenic (deliriant) in smaller doses – due to tropane alkaloid content and is used by Chilean machi (shamans) of the Mapuche–Huilliche people in traditional medicine, as a poison and to enter trance states.
DissociativeDissociatives, colloquially dissos, are a subclass of hallucinogens which distort perception of sight and sound and produce feelings of detachment – dissociation – from the environment and/or self. Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include dissociation, a general decrease in sensory experience, hallucinations, dream-like states or anesthesia.
HyoscyamineHyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and deadly nightshade. It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine. Brand names for hyoscyamine include Symax, HyoMax, Anaspaz, Egazil, Buwecon, Cystospaz, Levsin, Levbid, Levsinex, Donnamar, NuLev, Spacol T/S, and Neoquess.