Concept

Sedation

Related publications (9)

Quasi-Digital Biosensor-Interface for a Portable Pen to Monitor Anaesthetics Delivery

Sandro Carrara, Francesca Stradolini, Danilo Demarchi, Abuduwaili Tuoheti, Simone Aiassa

Monitoring of patient response to the anaesthetic drugs is an attractive improvement for achieving a correct balance of sedation level, increasing the chance of success in the right procedure of anaesthesia. Nowadays, there are no commercial tools able to ...

IEEE2019

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Giovanni De Micheli, Giovanni Boero, Francesca Stradolini, Irene Taurino, Tugba Kilic

In this work, we present a novel electrochemical cleaning procedure for long-term electrochemical monitoring of propofol by using boron-doped diamond (BDD) and pencil graphite electrode (PGE). Propofol is an anesthetic that is widely used for long-lasting ...

2018

Performance of Carbon Nano-Scale Allotropes in Detecting Midazolam and Paracetamol in Undiluted Human Serum

Giovanni De Micheli, Sandro Carrara, Francesca Stradolini, Irene Taurino, Ioulia Tzouvadaki, Nima Aliakbarinodehi, Sattar Akbari Nakhjavani

Nano-materials are highly exploited to enhance sensing performance of electrochemical electrodes by increasing the Electro-Active Surface Area (EASA). In this work, an analytical calculation of the deposited EASA is presented and experimentally validated b ...

2018

Towards 3D facial morphometry

Gabriel Louis Cuendet

In anesthesiology, the detection and anticipation of difficult tracheal intubation is crucial for patient safety. When undergoing general anesthesia, a patient who is unexpectedly difficult to intubate risks potential life-threatening complications with po ...

EPFL2017

Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex

Rolf Gruetter, Hongxia Lei

Barbiturates are regularly used as an anesthetic for animal experimentation and clinical procedures and are frequently provided with solubilizing compounds, such as ethanol and propylene glycol, which have been reported to affect brain function and, in the ...

Wiley-Blackwell2010

Forecasting respiratory rate in sedated patients with partial least squares regression

Jérémie Guignard

Remifentanil, like the other sedative drugs used to achieve conscious sedation, has an impact on the efficiency of patient ventilation. Since the quality of breathing has an indirect effect on blood O2 and CO2 concentrations, keeping patients' blood homeos ...

2009

Modeling the Gabaergic Action of Etomidate on the Thalamocortical System

Sean Lewis Hill

BACKGROUND: We have used a computational model of the thalamocortical system to investigate the effects of a GABAergic anesthetic (etomidate) on cerebral cortical and thalamic neuronal function. We examined the effects of phasic an tonic inhibition, as wel ...

2009

Effect of deep pentobarbital anesthesia on neurotransmitter metabolism in vivo: on the correlation of total glucose consumption with glutamatergic action

Rolf Gruetter, Hongxia Lei

The effect of deep barbiturate anesthesia on brain glucose transport, TCA cycle flux, and aspartate, glutamate, and glutamine metabolism was assessed in the rat brain using 13C nuclear magnetic resonance spectroscopy at 9.4 T in conjunction with [1-13C] gl ...

Nature Publishing Group2002

Adhesion prevention with ancrod released via a tissue-adherent hydrogel

Jeffrey Alan Hubbell

The objective of this investigation was to evaluate the effect of ancrod, a fibrinogenolytic protease from Malayan pit viper venom, locally delivered through a photopolymerized biodegradable hydrogel in preventing postoperative adhesions. The experimental ...

1996

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