Concept

The Chemical Basis of Morphogenesis

Related publications (24)

Numerical methods for nonlinear reaction-diffusion equations with traveling wave solutions

In this report, we first introduce operator splitting as a way to solve nonlinear reaction-diffusion PDEs. We then present a flux-limiting technique for anisotropic diffusion problems that allows to recover the discrete maximum principle. Finally, we imple ...

2014

In vitro lymphatic endothelial morphogenesis

Carolyn Yong Pullin

Cell organization into functional multicellular three-dimensional structures is a long-standing challenge. In particular, engineering of vascularized tissues requires both blood and lymphatic neovascular network formation in a simultaneous and coordinated ...

EPFL2011

Surface optofluidics

Demetri Psaltis, Andreas Vasdekis, Wuzhou Song, Jae-Woo Choi, Julien Cuennet, Luciano De Sio

Surfaces -defined as the interfaces between solids and liquids- have attracted much attention in optics and biology, such as total internal reflection imaging (TIRF) and DNA microarrays. Within the context of optofluidics however, surfaces have received li ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2010

Additive and global functions of HoxA cluster genes in mesoderm derivatives

Denis Duboule, Freddy Radtke, Ute Koch

Hox genes encode transcription factors that play a central role in the specification of regional identities along the anterior to posterior body axis. In the developing mouse embryo, Hox genes from all four genomic clusters are involved in range of develop ...

Elsevier2010

Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis

Cathrin Brisken, Renuga Devi Rajaram

Epithelial-mesenchymal interactions are key to skin morphogenesis and homeostasis. We report that maintenance of the hair follicle keratinocyte cell fate is defective in mice with mesenchymal deletion of the CSL/RBP-Jkappa gene, the effector of "canonical" ...

Cold Spring Harbor Laboratory Press2010

Adaptive Multiresolution Methods for the Simulation of Waves in Excitable Media

Ricardo Esteban Ruiz Baier

We present fully adaptive multiresolution methods for a class of spatially two-dimensional reaction-diffusion systems which describe excitable media and often give rise to the formation of spiral waves. A novel model ingredient is a strongly degenerate dif ...

Springer Verlag2010

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

Bruno Lemaitre, Nichole Broderick, Takayuki Kuraishi

ABSTRACT: BACKGROUND: Gut homeostasis is central to whole organism health, and its disruption is associated with a broad range of pathologies. Following damage, complex physiological events are required in the gut to maintain proper homeostasis. Previously ...

BioMed Central2010

A model-based block-triangular preconditioner for the Bidomain system in electrocardiology

Fabio Nobile

We introduce a preconditioner for the solution of the Bidomain system governing the propagation of action potentials in the myocardial tissue. The Bidomain model is a degenerate parabolic set of nonlinear reaction-diffusion equations. The nonlinear term de ...

Elsevier2009

Acquisition et recalage informatique d'images confocales de tissus denses

Nicolas Fête

Analysis of the 3D structure of a biological sample is an important step to model cell and tissue dynamics. As a model system, we set up to determine the number of nuclei in a follicular papilla using confocal imaging and 3D computer reconstruction. The fo ...

EPFL2008

Evolutionary morphogenesis for multi-cellular systems

Dario Floreano, Daniel Roggen, Diego Federici

With a gene required for each phenotypic trait, direct genetic encodings may show poor scalability to increasing phenotype length. Developmental systems may alleviate this problem by providing more efficient indirect genotype to phenotype mappings. A novel ...

2007

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