Publications related to Nucleotide excision repair

Increasing Availability in Distributed Storage Systems via Clustering

Michael Christoph Gastpar, Saeid Sahraei

We introduce the Fixed Cluster Repair System (FCRS) as a novel architecture for Distributed Storage Systems (DSS) that achieves a small repair bandwidth while guaranteeing a high availability. Specifically, we partition the set of servers in a DSS into s c ...

2018

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Didier Trono, Priscilla Turelli, Julien Léonard Duc, Sandra Eloise Kjeldsen, Annamaria Kauzlaric, Andrea Coluccio, Julien Paul André Pontis, Suk Min Jang, Benjamin Rauwel, Geneviève Almouzni

During cell division, maintenance of chromatin features from the parental genome requires their proper establishment on its newly synthetized copy. The loss of epigenetic marks within heterochromatin, typically enriched in repetitive elements, endangers ge ...

2018

Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors

Douglas Hanahan, Mohammad Sadegh Saghafinia, Giovanni Ciriello, Marco Mina

The discovery of cancer-associated alterations has primarily focused on genetic variants. Nonetheless, altered epigenomes contribute to deregulate transcription and promote oncogenic pathways. Here, we designed an algorithmic approach (RESET) to identify a ...

CELL PRESS2018

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage

Beat Fierz, Sinan Kilic, Iuliia Boichenko, Carolin Christine Lechner

The cellular response to DNA damage results in a signaling cascade that primes chromatin for repair. Combinatorial post-translational modifications (PTMs) play a key role in this process by altering the physical properties of chromatin and recruiting downs ...

2018

Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma

Jacques Fellay, Patrick Taffe

Background: Kaposi's sarcoma, the most common AIDS-related cancer, represents a major public concern in resource-limited countries. Single nucleotide polymorphisms within the Interferon lambda 3/4 region (IFNL3/4) determine the expression, function of IFNL ...

LIPPINCOTT WILLIAMS & WILKINS2018

Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces

Dominique Pioletti, Pierre-Etienne Bourban, Christophe Moser, Peyman Karami, Andreas Schmocker, Azadeh Khoushabi, Céline Samira Wyss, Martin Broome

Despite the development of hydrogels with high mechanical properties, insufficient adhesion between these materials and biological surfaces significantly limits their use in the biomedical field. By controlling toughening processes, we designed a composite ...

2018

Hippo, TGF-beta, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

Bart Deplancke, Yu-Chen Tsai

Cytokine signaling is responsible for coordinating conserved epithelial regeneration and immune responses in the digestive tract. In the Drosophila midgut, Upd3 is a major cytokine, which is induced in enterocytes (EC) and enteroblasts (EB) upon oral infec ...

Public Library of Science2017

MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

Christian Iseli, Nicolas Mermod, Thomas Junier, Samuel Neuenschwander, Ioannis Xenarios

Untargeted plasmid integration into mammalian cell genomes remains a poorly understood and inefficient process. The formation of plasmid concatemers and their genomic integration has been ascribed either to non-homologous end-joining (NHEJ) or homologous r ...

2017

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria

Melanie Blokesch

Natural competence enables bacteria to take up exogenous DNA. The evolutionary function of natural competence remains controversial, as imported DNA can act as a source of substrates or can be integrated into the genome. Exogenous homologous DNA can also b ...

Nature Publishing Group2017

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Nucleotide excision repair

Increasing Availability in Distributed Storage Systems via Clustering

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage

Telomeric states in cancer development

Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma

Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces

Hippo, TGF-beta, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria

Graph Chatbot

Chat with Graph Search

Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces

Increasing Availability in Distributed Storage Systems via Clustering

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors

Interferon lambda 3/4 polymorphisms are associated with AIDS-related Kaposi's sarcoma

Telomeric states in cancer development

Hippo, TGF-beta, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria