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Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-r ...
The KZFP/KAP1 (Krüppel associated box zinc finger proteins/KRAB-associated protein 1) complex is a transcriptional repressor that triggers the deposition of heterochromatin (H3K9me3) and DNA methylation. The main targets of the KZFP/KAP1 complex are transp ...
In Europe about 2 million people work and live in two different countries. While at the European scale cross-border workers only account for a limited portion of the working-age population, in some regions cross-border work takes a huge importance. In thes ...
Socio-economic related properties of a city grow faster than a linear relationship with the population, in a log–log plot, the so-called superlinear scaling. Conversely, the larger a city, the more efficient it is in the use of its infrastructure, leading ...
In an environment subject to anthropogenic pressures, the understanding of lakes is crucial as they are essential for ecosystems and represent a source of the scarce accessible freshwater existing on Earth. Water quality management is especially designed t ...
The efforts made to plan cities in emerging and developing countries are confronted to multiple issues, especially in small and middle-sized cities, which can be considered as poor through several criteria: socio-economic level of majority of population; l ...
Reproductive output and cognitive performance decline in parallel during aging, but it is unknown whether this reflects a shared genetic architecture or merely the declining force of natural selection acting independently on both traits. We used experiment ...
With an ever growing population the city of Lausanne has a need to monitor and preserve its main water source, the lake. Permanent discharge from combined sewer over ows (CSO) and the waste water treatment plant have an impact on the Vidy Bay, making it th ...
Vaccine refusal can lead to renewed outbreaks of previously eliminated diseases and even delay global eradication. Vaccinating decisions exemplify a complex, coupled system where vaccinating behavior and disease dynamics influence one another. Such systems ...
Given the strong selective pressures often faced by populations when colonizing a novel habitat, the level of variation present on which selection may act is an important indicator of adaptive potential. While often discussed in an ecological context, this ...
