Publications related to Protocell

Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report

Michele De Palma, Ferdinando Pucci, Qin Zhang

Extracellular vesicles (EVs) are small, lipid-bilayer-bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs, and proteins. Once released in the extracellular environment, EVs can act as messengers locally ...

WILEY2023

Cholesterol-Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery

Francesco Stellacci, Paulo Henrique Jacob Silva, Ester Canepa, Giulia Rossi

Membrane fusion is essential for the basal functionality of eukaryotic cells. In physiological conditions, fusion events are regulated by a wide range of specialized proteins, operating with finely tuned local lipid composition and ionic environment. Fusog ...

WILEY-V C H VERLAG GMBH2023

Liposomes and Lipid Droplets Display a Reversal of Charge-Induced Hydration Asymmetry

Sylvie Roke, Nathan Dupertuis, Saranya Pullanchery Sankara Narayanan

The unique properties of water are critical for life. Water molecules have been reported to hydrate cations and anions asymmetrically in bulk water, being a key element in the balance of biochemical interactions. We show here that this behavior extends to ...

Washington2023

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Francesco Stellacci, Paulo Henrique Jacob Silva, Xufeng Xu, Camilla Servidio

Amphiphilic gold core nanoparticles (AmNPs) striped with hydrophilic 11-mercapto-1-undecanesulfonate (MUS) and hydrophobic 1-octanethiol (OT) ligands are promising candidates for drug carriers that passively and nondisruptively enter cells. Yet, how they i ...

Washington2023

Article Structure and functionality of a multimeric human COQ7:COQ9 complex

Matteo Dal Peraro, Luciano Andres Abriata

Coenzyme Q (CoQ) is a redox-active lipid essential for core metabolic pathways and antioxidant defense. CoQ is synthesized upon the mitochondrial inner membrane by an ill-defined "complex Q" metabolon. Here, we present structure-function analyses of a lipi ...

CELL PRESS2022

New Insights for Parasitic Effects of Label-Free Biosensors Based on Capacitive Micromachined Ultrasonic Transducers

Sandro Carrara, Zhengwen Jiang, Yihe Zhao, Jie Li

Capacitive micromachined ultrasonic transducers (CMUTs) are regarded as an attractive candidate in bio-applications such as imaging and molecule monitoring. However, the previous researches on biochemical sensing are mostly air-coupled application based on ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2022

Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

Yimon Aye, Jesse Poganik

With a lipid-rich environment and elevated oxygen consumption, the central nervous system (CNS) is subject to intricate regulation by lipid-derived electrophiles (LDEs). Investigations into oxidative damage and chronic LDE generation in neural disorders ha ...

FRONTIERS MEDIA SA2020

Single-molecule kinetics of pore assembly by the membrane attack complex

Georg Fantner, Adrian Pascal Nievergelt

The membrane attack complex (MAC) is a hetero-oligomeric protein assembly that kills pathogens by perforating their cell envelopes. The MAC is formed by sequential assembly of soluble complement proteins C5b, C6, C7, C8 and C9, but little is known about th ...

Springer2019

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

Jian Wang, Henning Paul-Julius Stahlberg, Amanda Jennifer Lewis

Parkinson's disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological hallmarks are Lewy bodies and Lewy neurites: neuronal inclusions immunopositive for the protein alph ...

Springer Science and Business Media LLC2019

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Protocell

Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report

Cholesterol-Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery

Liposomes and Lipid Droplets Display a Reversal of Charge-Induced Hydration Asymmetry

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Article Structure and functionality of a multimeric human COQ7:COQ9 complex

New Insights for Parasitic Effects of Label-Free Biosensors Based on Capacitive Micromachined Ultrasonic Transducers

Age- and gender-related differences in brain tissue microstructure revealed by multi-component T2 relaxometry

Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

Single-molecule kinetics of pore assembly by the membrane attack complex

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

Graph Chatbot

Chat with Graph Search

Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report

Single-molecule kinetics of pore assembly by the membrane attack complex

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Cholesterol-Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery

Liposomes and Lipid Droplets Display a Reversal of Charge-Induced Hydration Asymmetry

Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals

Article Structure and functionality of a multimeric human COQ7:COQ9 complex

Age- and gender-related differences in brain tissue microstructure revealed by multi-component T2 relaxometry

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

New Insights for Parasitic Effects of Label-Free Biosensors Based on Capacitive Micromachined Ultrasonic Transducers