Epidemic is a 1987 Danish experimental medical dark comedy-horror film co-written and directed by Lars von Trier; it is the second installment of Trier's Europa trilogy, following The Element of Crime (1984) and succeeded by Europa (1991). Co-written by Trier and Niels Vørsel, the film focuses on the screenwriting process. Vørsel and Trier play themselves, coming up with a last-minute script for a producer. The story is inter-cut with scenes from the film they write, in which Trier plays a renegade doctor trying to cure a modern-day epidemic. The film marks the first in a series of collaborations between Trier and Udo Kier. In a metafiction version of the film, divided into five days. On the first day of the protagonists, screenwriters Lars and Niels lose the only copy of a film script (Kommisæren Og Luderen, "The Policeman and the Whore", a reference to The Element of Crime). They begin to write a new script about an epidemic: the outbreak of a plague-like disease. Another protagonist is a doctor, Mesmer, who, against the will of the Faculty of Medicine of an unknown city, goes to the countryside to help people. During the next days, the facts of the script join the real-life events in which a similar disease starts to spread. Lars and Niels go to Germany, where they meet a man who describes the Allied bombing of Cologne during the Second World War. After the trip, Niels goes to a hospital where he undergoes a minor surgical procedure and while there tells Lars to go to see Palle, a pathologist who is performing an autopsy on a man who has recently died of an unknown disease. The last day, Lars and Niels have a dinner with their producer, to whom they reveal the end of the film, that Mesmer and his medical kit have spread the disease. The producer does not like the short twelve-page script, which has no violence, few deaths, and no subplots (which are common in Danish cinema). After that a hypnotist and a woman arrive in the house, to "help" writing the script, but the woman is overpowered by the visions of the script which are becoming real.