Concept

Critical period

Related publications (73)

Sparse, reliable, and long-term stable representation of periodic whisker deflections in the mouse barrel cortex

The rodent whisker system is a preferred model for studying plasticity in the somatosensory cortex (barrel cortex). Contrarily, only a small amount of research has been conducted to characterize the stability of neuronal population activity in the barrel c ...

Academic Press Inc Elsevier Science2015

Social deficits induced by peripubertal stress in rats are reversed by resveratrol

Maria del Carmen Sandi Perez, Olivia Zanoletti, Guillaume Poirier

Adolescence is increasingly recognized as a critical period for the development of the social system, through the maturation of social competences and of their underlying neural circuitries. The present study sought to test the utility of resveratrol, a di ...

2014

Development of movement-related intracortical inhibition in acute to chronic subcortical stroke

Friedhelm Christoph Hummel

A prospective longitudinal cohort study in stroke patients was performed to better understand the role of γ-aminobutyric acid-dependent intracortical inhibition (ICI) for recovery after stroke. ...

2014

Neuroenhancement of the aging brain: restoring skill acquisition in old subjects

Friedhelm Christoph Hummel

Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies. ...

Wiley-Blackwell2013

Extreme prematurity and intra uterine growth restriction effects in brain network topology at school age

Jean-Philippe Thiran, Elda Fischi Gomez, Djalel Eddine Meskaldji, François Lazeyras

Higher risk for long-term behavioral and emotional sequelae, with attentional problems (with or without hyperactivity) is now becoming one of the hallmarks of extreme premature (EP) birth and birth after pregancy conditions leading to poor intra uterine gr ...

2013

The Consequences of adolescent chronic unpredictable stress exposure on brain and behavior

Fiona Hollis

There is increasing evidence for adolescence as a time period vulnerable to environmental perturbations such as stress. What is unclear is the persistent nature of the effects of stress and how specific these effects are to the type of stressor. In this re ...

Elsevier2013

The aging motor system as a model for plastic changes of GABA-mediated intracortical inhibition and their behavioral relevance

Friedhelm Christoph Hummel

Since GABAA-mediated intracortical inhibition has been shown to underlie plastic changes throughout the lifespan from development to aging, here, the aging motor system was used as a model to analyze the interdependence of plastic alterations within the in ...

2013

Plastic modifications within inhibitory control networks induced by practicing a stop-signal task: an electrical neuroimaging study

Fosco Bernasconi

Inhibitory control refers to our ability to suppress ongoing motor, affective or cognitive processes and mostly depends on a fronto-basal brain network. Inhibitory control deficits participate in the emergence of several prominent psychiatric conditions, i ...

2013

Hyperconnectivity and Slow Synapses during Early Development of Medial Prefrontal Cortex in a Mouse Model for Mental Retardation and Autism

Michele Giugliano

Neuronal theories of neurodevelopmental disorders (NDDs) of autism and mental retardation propose that abnormal connectivity underlies deficits in attentional processing. We tested this theory by studying unitary synaptic connections between layer 5 pyrami ...

Oxford University Press2012

The timing of exploratory decision-making revealed by single-trial topographic EEG analyses

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Nicolas Bourdaud, Micah Murray, Athina Tzovara

Decision-making in an uncertain environment is driven by two major needs: exploring the environment to gather information or exploiting acquired knowledge to maximize reward. The neural processes underlying exploratory decision-making have been mainly stud ...

Elsevier2012

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