Publications related to Environmental toxicants and fetal development

Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction

Yohan Van de Looij, Maxime Olivier Baud

Fetal growth restriction (FGR) is a major complication of human pregnancy, frequently resulting from placental vascular diseases and prenatal malnutrition, and is associated with adverse neurocognitive outcomes throughout life. However, the mechanisms link ...

Wiley-Blackwell2016

Brain network characterization of high-risk preterm-born school-age children

Jean-Philippe Thiran, Alessandra Griffa, Elda Fischi Gomez, François Lazeyras

Higher risk for long-term cognitive and behavioral impairments is one of the hallmarks of extreme prematurity (EP) and pregnancy-associated fetal adverse conditions such as intrauterine growth restriction (IUGR). While neurodevelopmental delay and abnormal ...

Elsevier Sci Ltd2016

Structural Brain Connectivity in School-Age Preterm Infants Provides Evidence for Impaired Networks Relevant for Higher Order Cognitive Skills and Social Cognition

Jean-Philippe Thiran, Elda Fischi Gomez, Patric Hagmann, Djalel Eddine Meskaldji, François Lazeyras

Extreme prematurity and pregnancy conditions leading to intrauterine growth restriction (IUGR) affect thousands of newborns every year and increase their risk for poor higher order cognitive and social skills at school age. However, little is known about t ...

Oxford University Press2015

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

Rolf Gruetter, Yohan Van de Looij

Erythropoietin (EPO) has been recognized as a neuroprotective agent. In animal models of neonatal brain injury, exogenous EPO has been shown to reduce lesion size, improve structure and function. Experimental studies have focused on short course treatment ...

Public Library of Science2014

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Simona Frateschi, Friedrich Beermann, Roch-Philippe Charles, Aline Dousse

The serine protease CAP1/Prss8 is crucial for skin barrier function, lung alveolar fluid clearance and has been unveiled as diagnostic marker for specific cancer types. Here, we show that a constitutive knockout of CAP1/Prss8 leads to embryonic lethality. ...

Public Library of Science2013

Liver receptor homolog-1 is essential for pregnancy

Kristina Schoonjans

Successful pregnancy requires coordination of an array of signals and factors from multiple tissues. One such element, liver receptor homolog-1 (Lrh-1), is an orphan nuclear receptor that regulates metabolism and hormone synthesis(1). It is strongly expres ...

Nature Publishing Group2013

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

David Michael Suter, Mathurin Baquié

Neural differentiation of embryonic stem cells (ESC) is considered a promising model to perform in vitro testing for neuroactive and neurotoxic compounds. We studied the potential of a dual reporter murine ESC line to identify bioactive and/or toxic compou ...

2013

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

Didier Trono, Jeffrey Alan Hubbell, Melody Swartz, Witold Waldemar Kilarski, Joseph Rutkowski, Seung Tae Lee, Miriella Carmela Pasquier, Jong Eun Ihm, Vivianne Greenwood

Lymphatic vessels surround follicles within the ovary, but their roles in folliculogenesis and pregnancy, as well as the necessity of Lymphangiogenesis in follicle maturation and health, are undefined. We used systemic delivery of mF4-31C1, a specific anta ...

Elsevier Science Inc2013

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Environmental toxicants and fetal development

Fighting preterm birth with novel surgical tools and biomaterials engineering

Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction

Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury

Brain network characterization of high-risk preterm-born school-age children

Structural Brain Connectivity in School-Age Preterm Infants Provides Evidence for Impaired Networks Relevant for Higher Order Cognitive Skills and Social Cognition

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Liver receptor homolog-1 is essential for pregnancy

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

Graph Chatbot

Chat with Graph Search

Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction

Fighting preterm birth with novel surgical tools and biomaterials engineering

Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

Brain network characterization of high-risk preterm-born school-age children

Liver receptor homolog-1 is essential for pregnancy

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

Structural Brain Connectivity in School-Age Preterm Infants Provides Evidence for Impaired Networks Relevant for Higher Order Cognitive Skills and Social Cognition

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells