Concept

Pus

Related publications (8)

How to: Diagnose inborn errors of intrinsic and innate immunity to viral, bacterial, mycobacterial, and fungal infections

Background: Inborn errors of intrinsic and innate immunity constitute the focus of a growing research field that investigates the molecular mechanisms underlying susceptibility to infections previously not considered part of the spectrum of inborn errors o ...

ELSEVIER SCI LTD2022

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

Arne Seitz, Romain Guiet, Nicola Harris, Beatrice Volpe, Tiffany Babette Angélique Bouchery, Kathleen Shah, Manuel Kulagin, Mati André Marie Moyat

Hookworms cause a major neglected tropical disease, occurring after larvae penetrate the host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil extracellular traps (NETs), but whether they target hookworms during skin infec ...

CELL PRESS2020

Kicking Out Pathogens in Exosomes

Françoise Gisou van der Goot Grunberg, Oksana Andrei Sergeeva

Host-pathogen interactions involve a series of attacks and counter-attacks. Miao et al. show that, although some invading bacteria can take shelter in lysosomes by neutralizing their pH, this respite is temporary, as host cells can expel them in exosomes. ...

2015

A Comparison of Solar Photocatalytic Inactivation of Waterborne E. Coli Using Tris(2,2’-bipyridine)ruthenium(II), Rose Bengal and TiO2

César Pulgarin, Julian Andrés Rengifo Herrera

Background. The development of alternative processes to eliminate pathogenic agents in water is a matter of growing interest. Current drinking water disinfection procedures, such as chlorination and ozonation, can generate disinfection by-products with car ...

2007

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

Stewart Cole

The twin arginine translocation (Tat) system is used by many bacteria to export fully folded proteins containing cofactors. Here, we show genetically that this system is essential for Mycobacterium tuberculosis, as the tatAC operon and tatB genes could be ...

2006

[What can be expected from sequencing of the Mycobacterium tuberculosis genome?]

Stewart Cole

Mycobacterium tuberculosis, the scourge of humanity, is one of the most successful and scientifically challenging pathogens of all time. To catalyze the conception of new prophylactic and therapeutic interventions against tuberculosis, and to enhance our u ...

2000

Learning from the genome sequence of Mycobacterium tuberculosis H37Rv

Stewart Cole

Mycobacterium tuberculosis, the scourge of humanity, is one of the most successful and scientifically challenging pathogens of all time. To catalyse the conception of new prophylactic and therapeutic interventions against tuberculosis, and to enhance our u ...

1999

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Stewart Cole

Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tuberculosis, H37Rv, has been determined and analysed in ...

1998

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