Concept
Crista
Related publications (15)
In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Cristae membrane state plays a central role in regulating mitochondrial function and cellular metabolism. The protein Optic atrophy 1 (Opa1) is an important crista remodeler that exists as two forms in the mitochondrion, a membrane-anchored long form (l-Op ...
Springernature2024Uncovering and engineering the mechanical properties of the adhesion GPCR ADGRG1 GAIN domain
Patrick Daniel Barth, Florence Pojer, Mahdi Hijazi, Matthieu François Marfoglia, Louis Georges Baptiste Dumas
Key cellular functions depend on the transduction of extracellular mechanical signals by specialized membrane receptors including adhesion G-protein coupled receptors (aGPCRs). While recently solved structures support aGPCR activation through shedding of t ...
2023Monitoring and understanding Cu catalyst dissolution during CO2 electroreduction
Electrochemical reduction of carbon dioxide is a promising approach to decrease the amount of anthropogenic CO2 being released into the atmosphere, provided that a surplus of renewable electrical energy is available. Copper based materials are at the cente ...
EPFL2022Mitochondrial cristae modeled as an out-of-equilibrium membrane driven by a proton field
Anne-Florence Raphaëlle Bitbol
As the places where most of the fuel of the cell, namely, ATP, is synthesized, mitochondria are crucial organelles in eukaryotic cells. The shape of the invaginations of the mitochondria inner membrane, known as a crista, has been identified as a signature ...
2020High-throughput and adaptive super-resolution fluorescence microscopy of organelles
Fluorescence super-resolution microscopy has allowed unprecedented insight into the workings of biological systems below the diffraction limit of light. Over the past decade, it has overcome several challenges to deliver 3D, multi-color and faster imaging ...
EPFL2020Sources and variability of CO 2 in a pre‐alpine stream gravel bar
Gravel bars (GBs) contribute to carbon dioxide (CO2) emissions from stream corridors, with CO2 concentrations and emissions dependent on prevailing hydraulic, biochemical, and physicochemical onditions. We investigated CO2 concentrations and fluxes across ...
2019Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei
Mathilde Stéphanie Willemin, André Schneider
Mitochondria cannot form de novo but require mechanisms that mediate their inheritance to daughter cells. The parasitic protozoan Trypanosoma brucei has a single mitochondrion with a single-unit genome that is physically connected across the two mitochondr ...
2017