Concept
Dysplastic nevus syndrome
Related publications (21)
Monitoring Tyrosinase Expression in Non-metastatic and Metastatic Melanoma Tissues by Scanning Electrochemical Microscopy
Hubert Girault, Horst Pick, Andreas Stephan Lesch, Fernando Cortes Salazar, Tzu-En Lin, Alexandra Bondarenko
Although tremendous progress has been made in the diagnosis of melanoma, the identification of different stages of malignancy in a reliable way remains challenging. Current strategies rely on optical monitoring of the concentration and spatial distribution ...
Wiley-Blackwell2016Electrochemical sensing and imaging of biological samples
Implementation of analytical methods for biological samples (e.g. bacteria or mammalian cells) is of great importance for diagnosis and treatment of various diseases, as well as for environmental monitoring. However, analysing biological samples is a cumbe ...
EPFL2015VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics
Melody Swartz, Sachiko Hirosue, Amanda Waite Lund, Susan Thomas, Amine Issa, Vidya Raghavan
Tumor expression of the lymphangiogenic factor VEGF-C is correlated with metastasis and poor prognosis, and although VEGF-C enhances transport to the draining lymph node (dLN) and antigen exposure to the adaptive immune system, its role in tumor immunity r ...
Elsevier2012Exhaustion of tumor-specific CD8(+) T cells in metastases from melanoma patients
Bart Deplancke, Pedro Romero, Sunil Kumar Raghav, Nathalie Rufer, Lukas Baitsch
In chronic viral infections, CD8(+) T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of self- and tumor-specific CD8(+) T cells from mice and humans. Here we determined molecular profiles o ...
American Society for Clinical Investigation2011Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis
Summary We report on a systematic analysis of genotype-specific melanocyte UVR responses in transgenic mouse melanoma models along with tumour penetrance and comparative histopathology. pRb or p53 pathway mutations cooperated with Nras(Q61K) to transform m ...
2010Cutaneous melanoma in genetically modified animals
Cutaneous melanomas are tumors originating from skin melanocytes which are present in hair follicles, and interfollicular epidermal and dermal layers. Experimental work in model systems involves in silico, in vitro and in vivo analyses. Such models allow t ...
2007