Materia medica (lit.: 'medical material/substance') is a Latin term from the history of pharmacy for the body of collected knowledge about the therapeutic properties of any substance used for healing (i.e., medications). The term derives from the title of a work by the Ancient Greek physician Pedanius Dioscorides in the 1st century AD, De materia medica, 'On medical material' (Περὶ ὕλης ἰατρικῆς, Peri hylēs iatrikēs, in Greek).
The term materia medica was used from the period of the Roman Empire until the 20th century, but has now been generally replaced in medical education contexts by the term pharmacology. The term survives in the title of the British Medical Journals "Materia Non Medica" column.
The earliest known writing about medicine was a 110-page Egyptian papyrus. It was supposedly written by the god Thoth in about 16 BC. The Ebers papyrus is an ancient recipe book dated to approximately 1552 BC. It contains a mixture of magic and medicine with invocations to banish disease and a catalogue of useful plants, minerals, magic amulets and spells. The most famous Egyptian physician was Imhotep, who lived in Memphis around 2500 B.C. Imhotep's materia medica consisted of procedures for treating head and torso injuries, tending of wounds, and prevention and curing of infections, as well as advanced principles of hygiene.
In India, the Ayurveda is traditional medicine that emphasizes plant-based treatments, hygiene, and balance in the body's state of being. Indian materia medica included knowledge of plants, where they grow in all season, methods for storage and shelf life of harvested materials. It also included directions for making juice from vegetables, dried powders from herb, cold infusions and extracts.
The earliest Chinese manual of materia medica, the Shennong Bencao Jing (Shennong Emperor's Classic of Materia Medica), was compiled in the 1st century AD during the Han dynasty, attributed to the mythical Shennong. It lists some 365 medicines, of which 252 are herbs.