Publications related to Mitosis

Pombe's thirteen - control of fission yeast cell division by the septation initiation network

The septation initiation network (SIN) regulates aspects of cell growth and division in Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results in improper assembly of the contractile ring and failure of cytokinesis, gen ...

Company Of Biologists Ltd2015

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

Michaël Unser, Daniel Sage, Jacques Rougemont, Viesturs Simanis, Andrea Krapp, Daniel Andreas Schmitter, Anastasia Chasapi, Ioannis Xenarios

The Schizosaccharomyces pombe septation initiation network (SIN) regulates cytokinesis, and asymmetric association of SIN proteins with the mitotic spindle pole bodies (SPBs) is important for its regulation. Here, we have used semi-automated image analysis ...

Company Of Biologists Ltd2015

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

Pierre Gönczy, Georgios Hatzopoulos, Nicola Jane Dynes, Sheng Kai Pong

Centrioles are microtubule-based organelles crucial for cell division, sensing and motility. In Caenorhabditis elegans, the onset of centriole formation requires notably the proteins SAS-5 and SAS-6, which have functional equivalents across eukaryotic evol ...

2015

A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast

Thierry Laroche, Arne Seitz, Omaya Pierre Dudin, Raphaël Groux

Cell-cell fusion is essential for fertilization. For fusion of walled cells, the cell wall must be degraded at a precise location but maintained in surrounding regions to protect against lysis. In fission yeast cells, the formin Fus1, which nucleates linea ...

Rockefeller Univ Press2015

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Pierre Gönczy, Coralie Busso, Sachin Kotak

The positioning and the elongation of the mitotic spindle must be carefully regulated. In human cells, the evolutionary conserved proteins LGN/Gai1-3 anchor the coiled-coil protein NuMA and dynein to the cell cortex during metaphase, thus ensuring proper s ...

2014

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak

Understanding the structure of interphase chromosomes is essential to elucidate regulatory mechanisms of gene expression. During recent years, high-throughput DNA sequencing expanded the power of chromosome conformation capture (3C) methods that provide in ...

Oxford University Press2014

Dma1-dependent degradation of SIN proteins during meiosis in Schizosaccharomyces pombe

Viesturs Simanis, Andrea Krapp

The Schizosaccharomyces pombe septation initiation network (SIN) is required for cytokinesis during vegetative growth and for spore formation during meiosis. Regulation of the SIN during mitosis has been studied extensively, but less is known about its mei ...

Company of Biologists2014

An impedance-based flow microcytometer for single cell morphology discrimination

Philippe Renaud, Ludovica Colella, Marjan Shaker

Cell shape is a fundamental biological feature, providing specific information about physiological or pathological cellular conditions. Most of the state-of-the-art microfluidic cytometers, however, only allow simple cell analysis, including viability stud ...

Royal Soc Chemistry2014

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Mitosis

Pombe's thirteen - control of fission yeast cell division by the septation initiation network

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

Unraveling the Physiological Role of Capillary Morphogenesis Gene 2 in Health and Disease

A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes

Dma1-dependent degradation of SIN proteins during meiosis in Schizosaccharomyces pombe

An impedance-based flow microcytometer for single cell morphology discrimination

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family

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Pombe's thirteen - control of fission yeast cell division by the septation initiation network

Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

Unraveling the Physiological Role of Capillary Morphogenesis Gene 2 in Health and Disease

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family

A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

Dma1-dependent degradation of SIN proteins during meiosis in Schizosaccharomyces pombe

An impedance-based flow microcytometer for single cell morphology discrimination

Models that include supercoiling of topological domains reproduce several known features of interphase chromosomes