Publications related to Acute decompensated heart failure

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

Sustained ryanodine receptor (RyR) Ca2+ leak is associated with pathological conditions such as heart failure or skeletal muscle weakness. We report that a single session of sprint interval training (SIT), but not of moderate intensity continuous training ...

NATURE PORTFOLIO2021

Biomechanics of diastolic dysfunction: a one-dimensional computational modeling approach

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Diastolic dysfunction (DD) is a major component of heart failure with preserved ejection fraction (HFpEF). Accordingly. a profound understanding of the underlying biomechanical mechanisms involved in DD is needed to elucidate all aspects of HFpEF. In this ...

AMER PHYSIOLOGICAL SOC2020

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Alfio Quarteroni, Luca Dede', Christian Vergara, Marco Fedele

Systolic Anterior Motion (SAM) of the mitral valve - often associated with Hypertrophic Obstructive Cardiomyopathy (HOCM) - is a cardiac pathology in which a functional subaortic stenosis is induced during systole by the mitral leaflets partially obstructi ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells

Na Li

Brain natriuretic peptide (BNP) treatment increases heart function and decreases heart dilation after myocardial infarction (MI). Here, we investigated whether part of the cardioprotective effect of BNP in infarcted hearts related to improved neovascularis ...

ELIFE SCIENCES PUBLICATIONS LTD2020

Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

Alfio Quarteroni, Francesco Regazzoni

Cardiac in silico numerical simulations are based on mathematical models describing the physical processes involved in the heart function. In this review paper, we critically survey biophysically-detailed mathematical models describing the subcellular mech ...

SPRINGER SINGAPORE PTE LTD2020

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Gerardo Turcatti, Benjamin Rappaz, Fabien Kuttler, Bokyoung Kim, Pierre Marquet

We use quantitative phase digital holographic microscopy (QP-DHM) to image and quantify the beating movement of cardiomyocytes, derived from induced pluripotent stem cells (iPSCs), in control and drug-treated conditions. The development of an analysis algo ...

AMER CHEMICAL SOC2020

Investigating the variability of cardiac pulse artifacts across heartbeats in simultaneous EEG-fMRI recordings: A 7T study

Rolf Gruetter, João Pedro Forjaco Jorge, Lucie Bréchet

Electroencephalography (EEG) recordings performed in magnetic resonance imaging (MRI) scanners are affected by complex artifacts caused by heart function, often termed pulse artifacts (PAs). PAs can strongly compromise EEG data quality, and remain an open ...

2019

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara, Emine Can

Chemotherapy cocktails containing doxorubicin produce irreversible cardiotoxic side effects that may progress to heart failure, which can only be avoided through dose limitation of the chemotherapeutic agents. Increasing evidence suggest that cardiac dysfu ...

2017

A Patient-Specific Methodology for Prediction of Paroxysmal Atrial Fibrillation Onset

David Atienza Alonso, Jean-Marc Vesin, Amir Aminifar, Adrian Luca, Sasan Yazdani, Elisabetta De Giovanni

In spite of the progress in management of Atrial Fibrillation (AF), this arrhythmia is one of the major causes of stroke and heart failure. The progression of this pathology from a silent paroxysmal form (PAF) into a sustained AF can be prevented by predic ...

2017

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Acute decompensated heart failure

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

Biomechanics of diastolic dysfunction: a one-dimensional computational modeling approach

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells

Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Investigating the variability of cardiac pulse artifacts across heartbeats in simultaneous EEG-fMRI recordings: A 7T study

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

A Patient-Specific Methodology for Prediction of Paroxysmal Atrial Fibrillation Onset

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Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

Biomechanics of diastolic dysfunction: a one-dimensional computational modeling approach

A Patient-Specific Methodology for Prediction of Paroxysmal Atrial Fibrillation Onset

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Investigating the variability of cardiac pulse artifacts across heartbeats in simultaneous EEG-fMRI recordings: A 7T study

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells

Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress