Concept

Axon guidance

Related publications (125)

When does a volume of a bundle achieve saturation? A microstructure informed tractography study

Jean-Philippe Thiran, Gabriel Girard, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Maxime Descoteaux

Volumetric analysis of bundles derived from tractography is a popular statistical measure used in neurological disorder studies. Recent research performed by Gauvin shows that different bundles saturate with different tractography parameters, however, to a ...

2017

Surface-enhanced tractography (SET)

Gabriel Girard, Alessandro Daducci, Maxime Descoteaux

In this work, we exploit the T1 weighted image in conjunction with cortical surface boundary to improve the precision of tractography under the cortex. We show that utilizing the cortical interface and a surface flow, to model the superficial white matter ...

Elsevier2017

Parallel pathways from whisker and visual sensory cortices to distinct frontal regions of mouse neocortex

Carl Petersen, Varun Sreenivasan, Céline Matéo, Alexandros Kyriakatos

The spatial organization of mouse frontal cortex is poorly understood. Here, we used voltage-sensitive dye to image electrical activity in the dorsal cortex of awake head-restrained mice. Whisker-deflection evoked the earliest sensory response in a localiz ...

SPIE-Intl Soc Optical Eng2017

Group Decisions Influence Emergence and Regulation of Leaders during Collective Migration of Epithelial Cells

Medhavi Vishwakarma

Collective migration is a central event involving coordinated movement of several individuals. One of the critical events during collective migration is the emergence of leading individuals, who provide directional guidance for the group movement. While on ...

EPFL2017

Multi-Modal Optical Imaging of the Cerebellum in Animals

Graham Knott, Ludovico Silvestri

Thanks to their flexibility, optical techniques could be the key to explore anatomy, plasticity, and functionality of the cerebellum. As an example, an in vivo analysis of the dynamic remodeling of cerebellar axons by nonlinear microscopy can provide funda ...

Springer2016

Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth

Suboptimal axonal regeneration contributes to the consequences of nervous system trauma and neurodegenerative disease, but the intrinsic mechanisms that regulate axon growth remain unclear. We screened 50,400 small molecules for their ability to promote ax ...

2016

Astrocyte scar formation aids central nervous system axon regeneration

Mark Andrew Anderson, Michael V. Sofroniew

Transected axons fail to regrow in the mature central nervous system. Astrocytic scars are widely regarded as causal in this failure. Here, using three genetically targeted loss-of-function manipulations in adult mice, we show that preventing astrocyte sca ...

Nature Publishing Group2016

dHb9 Expressing Larval Motor Neurons Persist Through Metamorphosis to Innervate Adult-Specific Muscle Targets and Function in Drosophila Eclosion

Soumya Banerjee

The Drosophila larval nervous system is radically restructured during metamorphosis to produce adult specific neural circuits and behaviors. Genesis of new neurons, death of larval neurons and remodeling of those neurons that persistent collectively act to ...

Wiley-Blackwell2016

Quantitative and qualitative analysis of transient fetal compartments during prenatal human brain development

Elda Fischi Gomez, Jonas Richiardi

The cerebral wall of the human fetal brain is composed of transient cellular compartments, which show characteristic spatiotemporal relationships with major neurogenic events (proliferation, migration, axonal growth, dendritic differentiation, synaptogenes ...

Frontiers Research Foundation2016

Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control

Gioele La Manno

Despite the variety of physiological and target-related functions, little is known regarding the cellular complexity in the sympathetic ganglion. We explored the heterogeneity of mouse stellate and thoracic ganglia and found an unexpected variety of cell t ...

2016

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