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The engineering of cells for the production of fuels and chemicals involves simultaneous optimization of multiple objectives, such as specific productivity, extended substrate range and improved tolerance – all under a great degree of uncertainty. The achi ...
In patients undergoing coronary artery bypass grafting (CABG) surgery, post-operative atrial fibrillation (AF) occurs with a prevalence of up to 40%. The highest incidence is seen between the second and third day after the operation. Following cardiac surg ...
Given the global burden of tuberculosis, and more precisely of multidrug-resistant (MDR) tuberculosis (TB), one of the most pressing epidemiological issues is the study and prevention of transmission. The study aims to assess transmission within households ...
This paper discusses the results of an investigation into ways in which the safety risks of travel on road and rail interact with each other in Great Britain, other than through physical contact such as at level crossings. The two main foci of the paper ar ...
The ageing of existing structures and new innovative designs are increasing the necessity for a greater understanding of structural behaviour. A better understanding would improve effectiveness of activities such as assessing reserve capacity, evaluating l ...
Technical solutions aimed at limiting the impacts of urban wet-weather discharges are historically based on an end-of-pipe approach. The characteristics of wet-weather discharges, e. g. intermittent pollution loads, high variations in pollutant concentrati ...
Predicting the disinfection performance of a full-scale reactor in drinking water treatment is associated with considerable uncertainty. In view of quantitative risk analysis, this study assesses the uncertainty involved in predicting inactivation of Crypt ...
Cultures of vertebrate cells are widely applied in mechanistic studies in human toxicology as well as in toxicity identification in ecotoxicology. As in vitro models, they display many advantages over whole animal experimentation, pertaining to such charac ...
The overall goal of this dissertation is to contribute to the development of best available practice in environmental multimedia fate and multipathway exposure modelling for human health and ecosystem impacts, addressing several important aspects. Environm ...
At low flow rate operation, Francis turbines feature a cavitating vortex rope in the draft tube resulting from the swirling flow of the runner outlet. The unsteady pressure field related to the precession of the vortex rope induces plane wave propagating i ...