Concept

Monoamine oxidase

Related publications (22)

Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression

Pierre Magistretti, Maria del Carmen Sandi Perez, Didier Trono, Maria Isabel Cordero Campana, Guillaume Poirier, Anna Claire Groner, Cristina Marquez Vega

Although adverse early life experiences have been found to increase lifetime risk to develop violent behaviors, the neurobiological mechanisms underlying these long-term effects remain unclear. We present a novel animal model for pathological aggression in ...

Nature Publishing Group2013

Sensing hydrogen peroxide by carbon nanotube/horseradish peroxidase bio-nanocomposite

László Forró, Arnaud Magrez, Endre Horvath, Klara Hernadi

H2O2 is a product of reactions catalysed by several oxidase enzymes and it is essential in environmental and pharmaceutical analyses. The most commonly used enzyme in understanding the biological behaviour of catalysed oxidation of H2O2 is horseradish pero ...

Wiley-V C H Verlag Gmbh2013

Synthetic calibrators for the analysis of sulfoconjugated metanephrines in urine: hydrolysis conditions revisited

Sandrine Gerber, Jonathan Simonin

Background: The quantification of total (free + sulfated) metanephrines in urine is recommended to diagnose pheochromocytoma. Urinary metanephrines include metanephrine itself, normetanephrine and methoxytyramine, mainly in the form of sulfate conjugates ( ...

Elsevier2012

MAOA-L carriers are better at making optimal financial decisions under risk

Genes can affect behaviour towards risks through at least two distinct neurocomputational mechanisms: they may affect the value assigned to different risky options, or they may affect the way in which the brain adjudicates between options based on their va ...

2011

Neurobiological Mechanisms Involved in the Establishment and Maintenance of Dominance Hierarchies and its Modulation by Stress in Rats

Maria del Carmen Sandi Perez, Marjan Timmer

Stress can have a strong and long lasting effect on the establishment and maintenance of dominance hierarchies in rats. When two rats of a pair have not been stressed (non-stressed pair) before a first social encounter, they establish a dominance hierarchy ...

EPFL2011

Surface Assembly of Catechol-Functionalized Poly(l-lysine)-graft-poly(ethylene glycol) Copolymer on Titanium Exploiting Combined Electrostatically Driven Self-Organization and Biomimetic Strong Adhesion

Cyril Portmann, Karl Gademann

Nonfouling coatings, based on surface-tethered, hydrophilic polymer chains, have widespread application in areas such as biosensing, medical devices, and biotechnology. Self-organization of polymers is a particularly attractive approach given its simplicit ...

2010

The organometallic route to benzylamine type monoamine oxidase inhibitors

N-Methyl-N-(2-propynyl)piperonylamine can be simultaneously lithiated at the terminal acetylenic and at that arom. position which is flanked by both the side chain and an oxygen atom. Under carefully established conditions, the metal occupying the latter o ...

1998

Transforming growth factor-beta1 inhibits basal melanogenesis in B16/F10 mouse melanoma cells by increasing the rate of degradation of tyrosinase and tyrosinase-related protein-1

Friedrich Beermann

Current evidence suggests that melanogenesis is controlled by epidermal paracrine modulators. We have analyzed the effects of transforming growth factor-beta1 (TGF-beta1) on the basal melanogenic activities of B16/F10 mouse melanoma cells. TGF-beta1 treatm ...

1997

Investigation on the structure of the active site of monoamine oxidase-B by affinity labeling with the selective inhibitor lazabemide and by site-directed mutagenesis

Ursula Röthlisberger

The structural features of the active site of human monoamine oxidase B (MAO-B) were investigated by affinity labeling and site-directed mutagenesis. The pseudosubstrate inhibitor N-[2-aminoethyl]-5-chloro-2-pyridine carboxamide HCl (lazabemide) can be irr ...

1996

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA

Michel Aguet

Deficiency in monoamine oxidase A (MAOA), an enzyme that degrades serotonin and norepinephrine, has recently been shown to be associated with aggressive behavior in men of a Dutch family. A line of transgenic mice was isolated in which transgene integratio ...

1995

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