Alcmaeon of Croton (ælkˈmiːɒn; Ἀλκμαίων ὁ Κροτωνιάτης, Alkmaiōn, gen.: Ἀλκμαίωνος; fl. 5th century BC) was an early Greek medical writer and philosopher-scientist. He has been described as one of the most eminent natural philosophers and medical theorists of antiquity and he has also been referred to as "a thinker of considerable originality and one of the greatest philosophers, naturalists, and neuroscientists of all time." His work in biology has been described as remarkable, and his originality made him likely a pioneer. Because of difficulties dating Alcmaeon's birth, his importance has been neglected. Alcmaeon was born in Croton, Magna Graecia, and was the son of Peirithous. Alcmaeon is said by some to have been a pupil of Pythagoras, and he is believed to have been born c. 510 BC. Although he wrote primarily about medical topics, there is some suggestion that he was a philosopher of science, not a physician. He also practiced astrology and meteorology. Nothing more is known of the events of his life. During Alcmaeon's time, the medical school in Magna Graecia was regarded as the most famous; illnesses were studied in a scientific and experimental manner. Alcmaeon was considered by many an early pioneer and advocate of anatomical dissection and was said to be the first to identify Eustachian tubes. His celebrated discoveries in the field of dissection were noted in antiquity, but whether his knowledge in this branch of science was derived from the dissection of animals or of human bodies is disputed. Calcidius, on whose authority the fact rests, merely says "qui primus exsectionem aggredi est ausus," and the word exsectio would apply equally well in either case; some modern scholars doubt Calcidius' word entirely. Alcmaeon also was the first to dwell on the internal causes of illnesses. It was he who first suggested that health was a state of equilibrium between opposing humors and that illnesses were because of problems in environment, nutrition and lifestyle.