Concept

Self-administration

Related publications (19)

Influence of sustained loading on resistance and deformation capacity of reinforced concrete members in compression

Aurelio Muttoni, Xhemsi Malja, Miguel Fernández Ruiz

As acknowledged explicitly or implicitly in most of current design codes, a high level of sustained loading has a detrimental effect on the concrete compressive strength. However, its beneficial effect in terms of deformation capacity is neglected in most ...

ERNST & SOHN2022

Resolving time conflicts in activity-based scheduling

Michel Bierlaire, Timothy Michael Hillel, Janody Pougala

In this paper, we present a novel activity-based scheduling model that combines a continuous optimisation framework for temporal scheduling decisions (i.e. activity timings and durations) with traditional discrete choice models for non-temporal choice dime ...

2021

Resolving time conflicts in activity-based scheduling: A case study of Lausanne

Michel Bierlaire, Timothy Michael Hillel, Janody Pougala

2021

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia

Erika Myrna Borcel Novoa

Although cocaine abuse is up to three times more frequent among schizophrenic patients, it remains unclear why this should be the case and whether sex influences this relationship. Using a maternal immune activation model of schizophrenia, we tested whethe ...

Pergamon-Elsevier Science Ltd2016

Implication of individual differences in glucocorticoid responsiveness to stress in the development of psychopathology-like behaviour and underlying neurobiology

Sophie Elizabeth Walker

The period around puberty is a critical window in development. It is a time of neuroendocrine and neuroanatomical lability, rendering individuals highly sensitive to stress. Indeed, early adversity increases risk for psychopathology. The mechanisms via whi ...

EPFL2016

Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner

Fiona Hollis

Epigenetic mechanisms, such as histone modifications, regulate responsiveness to drugs of abuse, such as cocaine, but relatively little is known about the regulation of addictive-like behaviors by DNA methylation. To investigate the influence of DNA methyl ...

Soc Neuroscience2015

The effects of extrinsic stress on somatic markers and behavior are dependent on animal housing conditions

Maria del Carmen Sandi Perez, Guillaume Poirier, Michael van der Kooij, Damien Sébastien Huzard

Properties of the environment play an important role in animal wellbeing and may modulate the effects of external threats. Whereas stressors can affect emotion and impair cognition, environmental enrichment may prevent the occurrence of such negative seque ...

Pergamon-Elsevier Science Ltd2015

Increased corticosterone in peripubertal rats leads to long-lasting alterations in social exploration and aggression

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Stamatina Tzanoulinou, Vandana Veenit

Stress during childhood and adolescence enhances the risk of psychopathology later in life. We have previously shown that subjecting male rats to stress during the peripubertal period induces long-lasting effects on emotion and social behaviors. As cortico ...

Frontiers Research Foundation2013

Role of the HPA axis in the long-term programming of social behaviors by peripuberty stress

Vandana Veenit

Stress during childhood and adolescence enhances the risk of psychopathology later in life. In fact, exposure to stress during this period is known to predispose individuals to the development of psychopathologies such as depression and anxiety disorders l ...

EPFL2013

Personality traits in rats predict vulnerability and resilience to developing stress-induced depression-like behaviors, HPA axis hyper-reactivity and brain changes in pERK1/2 activity

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Cristina Marquez Vega, Jorge Eduardo Castro Cifuentes, Shanaz Diessler

Emerging evidence indicates that certain behavioral traits, such as anxiety, are associated with the development of depression-like behaviors after exposure to chronic stress. However, single traits do not explain the wide variability in vulnerability to s ...

Elsevier2012

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