Publications related to Inactivated vaccine

Delivery of STING agonists for adjuvanting subunit vaccines

Li Tang, Bing Feng, Simon Bart M. Van Herck

Adjuvant is an essential component in subunit vaccines. Many agonists of pathogen recognition receptors have been developed as potent adjuvants to optimize the immunogenicity and efficacy of vaccines. Recently discovered cyclic GMP-AMP synthase-stimulator ...

ELSEVIER2021

Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity

Davide Demurtas

Author summary Human cytomegalovirus (HCMV) infection is the foremost viral cause of congenital birth defects. Attempts to vaccinate against HCMV brought moderate, though not sufficient, reduction in infection. Moreover, phase II clinical trial with gB for ...

PUBLIC LIBRARY SCIENCE2020

Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

Francesco Stellacci

The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well as mitigation of the spread of infection, all through large-scale approaches such as specific alternative antiviral methods and classical disinfection protocols. ...

AMER CHEMICAL SOC2020

Adaptation of Human Enterovirus to Warm Environments Leads to Resistance against Chlorine Disinfection

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Timothy R. Julian

Sunlight, temperature, and microbial grazing are among the environmental factors promoting the inactivation of viral pathogens in surface waters. Globally, these factors vary across time and space. The persistence of viral pathogens, and ultimately their e ...

2020

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

Maartje Martina Cornelia Bastings, Kaltrina Paloja, Alice Comberlato

Most vaccines developed today include only the antigens that best stimulate the immune system rather than the entire virus or microbe, which makes vaccine production and use safer and easier, though they lack potency to induce acceptable immunity and long- ...

ROYAL SOC CHEMISTRY2019

The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study

Andrea Rinaldo, Enrico Bertuzzo, Flavio Finger

Background Cholera prevention and control interventions targeted to neighbors of cholera cases (case-area targeted interventions [CATIs]), including improved water, sanitation, and hygiene, oral cholera vaccine (OCV), and prophylactic antibiotics, may be a ...

2018

Cross-resistance of UV- or chlorine dioxide-resistant echovirus 11 to other disinfectants

Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Qingxia Zhong, Rachele Ossola

The emergence of waterborne viruses with resistance to disinfection has been demonstrated in the laboratory and in the environment. Yet, the implications of such resistance for virus control remain obscure. In this study we investigate if viruses with resi ...

Frontiers Research Foundation2017

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Francesco Stellacci, Paulo Henrique Jacob Silva, Randy Patrick Carney, Valeria Cagno

Up to 80% of the cost of vaccination programmes is due to the cold chain problem (that is, keeping vaccines cold). Inexpensive, biocompatible additives to slow down the degradation of virus particles would address the problem. Here we propose and character ...

Nature Publishing Group2016

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Inactivated vaccine

Delivery of STING agonists for adjuvanting subunit vaccines

Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity

Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

Adaptation of Human Enterovirus to Warm Environments Leads to Resistance against Chlorine Disinfection

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study

Spatially explicit modeling of cholera epidemics

Genotypic, phenotypic and mechanistic insights into viruses with resistance to common water disinfectants

Cross-resistance of UV- or chlorine dioxide-resistant echovirus 11 to other disinfectants

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Graph Chatbot

Chat with Graph Search

Spatially explicit modeling of cholera epidemics

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Adaptation of Human Enterovirus to Warm Environments Leads to Resistance against Chlorine Disinfection

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

The potential impact of case-area targeted interventions in response to cholera outbreaks: A modeling study

Genotypic, phenotypic and mechanistic insights into viruses with resistance to common water disinfectants

Cross-resistance of UV- or chlorine dioxide-resistant echovirus 11 to other disinfectants