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The aim of this work is to understand the interactions and interphase formation mechanisms between a liquid aminosilane oligomer (γ -APS) and glass, steel or gold surfaces as a function of the pH of the liquid aminosilane. When basic liquid γ -APS (pH 11.4 ...
Adeno-associated virus (AAV) DNA, by mimicking a stalled replication fork, provokes a DNA damage response that can arrest cells in the G2/M phase of the cell-cycle. This response depends strictly on DNA damage signaling kinases ATR and Chk1. Here, we used ...
MOTIVATION: The ability of cells to complete mitosis with high fidelity relies on elaborate checkpoint mechanisms. We study S- and M-phase checkpoint responses in silico in the budding yeast with a stochastic dynamical model for the cell-cycle. We aim to p ...
Abstract—The practical adhesion of maleic anhydride grafted polyethylene (MAH-PE) to galvanised steel was studied using 3-point flexure tests, before and after hydrothermal ageing. Before bonding, the electro-galvanised steel was treated with γ -aminopropy ...
The transcription factor Myc plays a central role in the control of cellular proliferation. Myc expression is induced by growth factors in a pathway mediated by cellular Src (c-Src), but it is not clear whether Myc induction or activity is required for mal ...
The molecular mechanisms regulating the sexual development of malaria parasites from gametocytes to oocysts in their mosquito vector are still largely unexplored. In other eukaryotes, NIMA-related kinases (Neks) regulate cell cycle progression and have bee ...
American Society for Biochemistry and Molecular Biology2005
Bonding between polyolefins and steel is widely found in applications as diverse as steel wire/cord reinforced polymers, and automotive components where steel and thermoplastics are commonly used. As polyolefins are highly unreactive, because of their low ...
The septation initiation network (SIN) triggers the onset of cytokinesis in the fission yeast Schizosaccharomyces pombe by promoting contraction of the medially placed F-actin ring. SIN signaling is regulated by the polo-like kinase plo1p and by cdc2p, the ...
he oncoprotein SET/TAF-Ibeta is a histone chaperone which is involved in cell-cycle control and chromatin remodeling. Confocal laser scanning microscopy reveals that SET is localized in distinct foci of variable size throughout the nucleoplasm of interphas ...
A novel mutant screen in fission yeast has identified the 'ethanol dependent' protein etd1p as a potential link between the septation initiation network (SIN), which initiates cytokinesis, and the actomyosin contractile ring that drives separation of the t ...
