Concept

Pregabalin

Related publications (22)

GABAergic-like dopamine synapses in the brain

Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders. Despite this significance, the true biological nature of dopamine synap ...

Cambridge2023

A conditional GABAergic synaptic vesicle marker for Drosophila

Brian Donal McCabe

Background: Throughout the animal kingdom, GABA is the principal inhibitory neurotransmitter of the nervous system. It is essential for maintaining the homeostatic balance between excitation and inhibition required for the brain to operate normally. Identi ...

2022

Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

Rolf Gruetter, Hongxia Lei, Bernard Lanz, João Miguel das Neves Duarte, Antoine Timothée Cherix, Blanca Lizarbe Serra

PURPOSE: Determine the feasibility of (1) H-[(13) C] MRS in the mouse hypothalamus using a 14.1T magnet. METHODS: We optimized the design of a (1) H-[(13) C] surface coil to maximize the signal-to-noise ratio of (1) H-[(13) C] MRS in the mouse hypothalamus ...

2018

Modeling and treatment optimization of pharmaceutically active compounds by the photo-Fenton process: The case of the antidepressant Venlafaxine

César Pulgarin, Sami Rtimi, Stefanos Giannakis, Idriss Hendaoui

In this study, the anti-depressant Venlafaxine, a new emerging contaminant of interest for the Swiss legislation, was subjected to systematic degradation. In order to develop an efficient framework for the treatment of emerging contaminants at industrial s ...

Elsevier Sci Ltd2017

Solar photo-Fenton and UV/H2O2 processes against the antidepressant Venlafaxine in urban wastewaters and human urine. Intermediates formation and biodegradability assessment

Hubert Girault, César Pulgarin, Dominique Grandjean, Luiz Felippe De Alencastro, Stefanos Giannakis, Milica Jovic, Idriss Hendaoui

In this work, the use of Advanced Oxidation Processes (AOPs) against the degradation of an emerging contaminant has been subjected under systematic investigation. The optimization of treatment of the anti- depressant drug Venlafaxine (VFA) was performed, u ...

Elsevier Science Sa2017

Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate

Mats Julius Stensrud

There is compelling evidence that glutamate can act as a cotransmitter in the mammalian brain. Interestingly, the third vesicular glutamate transporter (VGLUT3) is primarily found in neurons that were anticipated to be nonglutamatergic. Whereas the functio ...

2015

Degradation of Eight Relevant Micropollutants in Different Water Matrices by Neutral Photo-Fenton Process under UV254 and Simulated Solar Light Irradiation – a comparative study

César Pulgarin, Andrzej Sienkiewicz, Dominique Grandjean, Luiz Felippe De Alencastro

This is a comparative study of photolytic degradation under exposure to UV254 nm and solar-simulator irradiation of a mixture of eight equally concentrated relevant micropollutants in the presence of H2O2 and Fe(II) in ultrapure water, Lake Geneva water, a ...

Elsevier Science Bv2014

Altered Gaba And Somatostatin Modulation Of Proprioceptive Feedback After Spinal Cord Injury In Lamprey

David Parker

While various changes occur after spinal cord lesions, their influence on functional recovery is generally unclear. We have shown changes in proprioceptor and locomotor network properties below lesion sites in the lamprey spinal cord. The proprioceptive sy ...

Pergamon-Elsevier Science Ltd2013

Combined Cr and S poisoning in solid oxide fuel cell cathodes

Jan Van Herle, Aïcha Hessler-Wyser, Quentin Thomas Jeangros, Zacharie Wuillemin, Josef Andreas Schuler, Caroline Calderone

This work aims to compare the effect of combined chromium and sulfur contaminating conditions to the Cr contamination alone on the Cr poisoning mechanisms in (La,Sr)MnO3-(Zr,Y)O-2 solid oxide fuel cell (SOFC) cathodes. Whereas Cr2O3 and (Cr,Mn)(3)O-4 are f ...

Elsevier2012

GABA Signaling Promotes Synapse Elimination and Axon Pruning in Developing Cortical Inhibitory Interneurons

Graham Knott, Yu Fu

Accumulating evidence indicates that GABA acts beyond inhibitory synaptic transmission and regulates the development of inhibitory synapses in the vertebrate brain, but the underlying cellular mechanism is not well understood. We have combined live imaging ...

2012

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