Concept

Osteoporosis

Related publications (114)

Improving delamination resistance through tailored defects

Delamination is a well-known damage mode exhibited by laminated composites which has been extensively studied in unidirectional laminates (UD). In this work, a novel strategy consisting of the introduction of a small interlaminar defect to enhance the frac ...

2020

Systemic Risk in Networks with a Central Node

Damir Filipovic, Léo Hamed Amini

We examine the effects on a financial network of clearing all contracts though a central node (CN), thereby transforming the original network into a star-shaped one. The CN is capitalized with external equity and a guaranty fund. We introduce a structural ...

SIAM PUBLICATIONS2020

Patellar bone strain after total knee arthroplasty is correlated with bone mineral density and body mass index

Dominique Pioletti, Alexandre Terrier, Adeliya Latypova, Elham Taghizadeh, Philippe Büchler

Patella-related complications after total knee arthroplasty (TKA) remain a major clinical concern. Previous studies have suggested that increased postoperative patellar bone strain could be related to such complications, but there is limited knowledge on p ...

2019

Automated CT bone segmentation using statistical shape modelling and local template matching

Alexandre Terrier, Alain Farron, Elham Taghizadeh, Philippe Büchler

Accurate CT bone segmentation is essential to develop chair-side manufacturing of implants based on additive manufacturing. We herewith present an automated method able to accurately segment challenging bone regions, while simultaneously providing anatomic ...

2019

Non-setting, injectable biomaterials containing particulate hydroxyapatite can increase primary stability of bone screws in cancellous bone

Dominique Pioletti, Ulrike Kettenberger, Jorge Solana Munoz

BACKGROUND: Fracture fixation in weak bone is still a clinical challenge. Screw augmentation was shown to successfully increase their primary stability. The currently used calcium phosphate or polymeric bone cements, however, present important drawbacks su ...

2018

Fatigue as the missing link between bone fragility and fracture

Dominique Pioletti, Vincent Stadelmann, Claire Acevedo

The prevention of fragility fractures in bone—pathologic fractures resulting from daily activity and mostly occurring in the elderly population—has been a long-term clinical quest. Recent research indicating that falls in the elderly might be the conse- qu ...

2018

Effect of a collar on subsidence and local micromotion of cementless femoral stems: in vitro comparative study based on micro-computerised tomography

Dominique Pioletti, Alexandre Terrier, Valérie Hélène Emilie Malfroy Camine

Purpose The aim of this study is to quantitatively compare the difference in primary stability between collarless and collared versions of the same femoral stem. Specifically, we tested differences in subsidence and micromotion. Methods Collarless and coll ...

Springer Verlag2018

Create a Finite Element model of experiment involving cadaveric scapulae

Raphaëlle Peyraud

Hypothesis: Nowadays, the number of people suffering from shoulder osteoarthritis increases as the population is ageing. An end-stage treatment is the total shoulder arthroplasty (TSA), but it still suffers from a high failure rate in comparison to other j ...

2018

The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool

Freddy Radtke

Notch signaling is critical for osteoblastic differentiation; however, the specific contribution of individual Notch ligands is unknown. Parathyroid hormone (PTH) regulates the Notch ligand Jagged1 in osteoblastic cells. To determine if osteolineage Jagged ...

Wiley2017

Importance of trabecular anisotropy in finite element predictions of patellar strain after Total Knee Arthroplasty

Dominique Pioletti, Alexandre Terrier, Adeliya Latypova

Patellar fracture and anterior knee pain remain major complications after Total Knee Arthroplasty (TKA). Patient-specific finite element (FE) models should help improve understanding of these complications through estimation of joint and bone mechanics. Ho ...

Elsevier2017

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