Concept
Estrogen
Related people (21)
Cathrin Brisken
Cathrin Brisken, MD, PhD, is Associate Professor of Life Sciences at the Swiss Federal Institute of Technology Lausanne (EPFL). Dr. Brisken is internationally recognized for her work on endocrine control of mammary gland development and breast carcinogenesis.
Dr. Brisken received her MD and her PhD degree in Biophysics from the Georg August University of Göttingen, Germany. She completed her postdoctoral work in cancer biology with Dr. R.A. Weinberg at the Whitehead Institute of Biomedical Research in Cambridge, MA, USA. She previously held appointments at the Cancer Center of the Massachusetts General Hospital, Harvard Medical School, Boston and the Swiss Institute for Experimental Cancer Research (ISREC).
Research in Dr. Brisken’s laboratory focuses on the cellular and molecular underpinnings of estrogen and progesterone receptor signaling in the breast and the respective roles of these hormones and hormonally active compounds in carcinogenesis. The aim is to understand how recurrent exposures to endogenous and exogenous hormones contribute to breast carcinogenesis in order to better prevent and treat the disease. The laboratory has pioneered in vivo approaches to genetically dissect the role of the reproductive hormones in driving mouse mammary gland development and shown how they control intercellular communication. Dr. Brisken’s group has developed ex vivo and humanized mouse models using patient samples to study hormone action in human tissues in normal settings and during disease progression.
Dr. Brisken is member of the International Breast Cancer Study Group (IBCSG) Biological Protocol Working Group. She served as Dean of EPFL Doctoral School (more than 2000 PhD students in 18 PhD programs), as member of the Hinterzartener Kreis, the oncology think-tank associated with the German Science Foundation, and numerous Swiss, European, and AACR committees. She co-founded the International Cancer Prevention Institute.
Johan Auwerx
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Urs von Gunten
URS VON GUNTEN
born in Baden (Switzerland) on 20/10/1959
RESEARCH INTERESTS
Drinking water quality and water treatment. Unit processes and process combinations (adsorption processes, membrane processes, oxidation processes). Chemical oxidation and advanced oxidation processes: kinetics and mechanisms of formation of disinfection by-products and degradation of micropollutants. Assessment of toxicology of of transformation products. Biogeochemical processes in riverbank filtration systems. In situ and out-of-ground treatment of groundwaters
EDUCATION
Diploma Swiss Federal Institute of Technology (ETH) Zürich, Department of Chemistry,Switzerland, 1983
Ph.D.Swiss Federal Institute of Technology (ETH) Zürich, Switzerland, 1989.
AWARDS AND FELLOWSHIPS
2018 Clarivate Analytics Highly Cited Researcher
2015 Thomson Reuters Highly Cited Researcher
2015 Recipient of the Harvey Rosen Award 2015 of the International Ozone Association
2015 Professorship under the Chinese Academy of Sciences President’s International Fellowship Initiative for Distinguished Scientists
2014 Thomson Reuters Highly Cited Researcher
2013 Distinguished Lecturer for AEESP at the American Water Works Association Annual Conference, Denver, June 10, 2013
2012-to date Adjunct Professor at the Gwangju Institute of Science and Technology, Korea
2011 Full Professor at the Swiss Federal Institute of Technology, Lausanne (EPFL)
2010 Adjunct Professor at the State Key Laboratory of Environmental Aquatic
Chemistry, Chinese Academy of Sciences
2010 Adjunct Professor at the Curtin University of Technology, Perth,
Australia
2007 Honorary Professorship at the Harbin Institute of Technology, Harbin,
China
2007 Recipient of the Harvey Rosen Award 2007 of the International Ozone
Association
2007 Environmental Science and Technology Excellence in Review Award
2006 Professor title at ETHZ, Department of Environmental Sciences
2001 Recipient of the Harvey Rosen Award 2001 of the International Ozone
Association
1999 Recipient of the Marteen Schalekamp Award 1999 of the IWSA
1993 Recipient of a short-term fellowship of the Swiss National Science
Foundation in 1993 and 1994
1993 EERO short-term fellowship-holder
PROFESSIONAL RECORD
2013-2016 Head of transdisciplinary project “Regional Water Supply Basel Country 21”, Eawag
2010-2017 Head of Competence Center for Drinking Water, Eawag
2008/2009 Visiting Professor at the Curtin Water Quality Research Centre,
Curtin University of Technology, Perth, Australia
2004-to date Deputy head of department Water Resources and Drinking Water,
Eawag
2004-2008 Head of the cross-cutting project Drinking water for the 21st
century, Eawag
2000 2004 Head of department Water Resources and Drinking Water, Eawag
2000/2001 Sabbatical at University of Colorado, Boulder
1998 - 1999 Head of department of Chemistry, Eawag
1995 - 2011 Lecturer at Swiss Federal Institute of Technology (ETH) Zürich,
Switzerland.
1995- to date Group leader of the drinking water group of the chemistry
department at Eawag
1994/93 Visiting Scientist at the International Research Center for
Water and Environment of Lyonnaise des Eaux (8 months),
CIRSEE, Le Pecq, France
since 1992 Research Scientist at Eawag
1989 - 1991 Postdoctoral Researcher at Eawag
1984 - 1989 Research Assistant, Swiss Federal Institute of Technology,
Zürich
EDITORIAL ACTIVITIES
Associate Editor Environmental Science and Technology (2010/2011)
Guest Editor Water Research for special issue on Emerging
Contaminants (2010)
Guest Editor Journal of water supply: Research and
Technology-Aqua for a special issue on Oxidation Processes (2008)
Member of the editorial board of the journal Ozone: Science and Engineering.
Member of the editorial board of Journal of water supply: Research and Technology-Aqua.
FORMER PROFESSIONAL ACTIVITIES
2016 Co-organizer of PEAK seminar ”Neue Herausforderungen und Lösungsansätze in der Wasserversorgung – Fallbeispiele aus dem Kanton BL”. Dübendorf, November 11, 2016
2015 Organizer of PEAK seminar “Micropollutants in drinking water”, Dübendorf, October 30
2014 Co-organizer of the Eawag Infotag “Wasserversorgung und Uferfiltration – ein System unter Druck?” Dübendorf, September 9, 2014
2014 Co-organizer of a Symposium “Advanced oxidation processes for water treatment” 5th EuCheMS Chemistry Congress 2014, Aug. 31 – Sept. 4, Istanbul, Turkey, 2014
2013 Co-Organizer of PEAK seminar on “Oxidation and Disinfection Processes”, Aug. 30, Dübendorf
2013 Co-Organizer of the Micropoll & Ecohazard Conference, Zürich, June 17-19, 2013
2013 Co-Organizer of the session “Advanced Oxidation – Technologies and Applications, Leading Edge Technology (LET) Conference, Bordeaux, June 2-6, 2013
2011 Co-Organizer of Korean-Swiss Science Days in Zürich “Water for the Future”, ETHZ, November 9-10, 2011.
2010 Co-Organizer of an international symposium “Oxidation processes in natural and technical aquatic systems” in honour of Jürg Hoigné’s 80 birthday, Eawag, May 21, 2010.
2010 Co-Organizer of 23. Mülheimer Wassertechnisches Seminar “Möglichkeiten und Grenzen von oxidativen Prozessen in der Wasserreinhaltung”, March 11, 2010, IWW, Mülheim an der Ruhr
2008 Co-Organizer of the Eawag Infotag 2008 “Vom Gewässer ins Glas”, Sept. 12, 2008, Eawag, Dübendorf
2008 Organizing committee of Leading Edge Technology Conference (LET), Zürich, June 1-4, 2008.
2008 Co-organizer of Sino-Swiss workshop “Water Resources Management and Drinking Water Quality”, Harbin Institute of Technology, Harbin, China, January, 2008
2007 Organizer of Wave21 seminar on “New insights in the field of drinking water treatment”, Dübendorf, Sept. 14, 2007.
2007 Co-organizer of a symposium entitled “Sustainability in Water Supply: Advances in Oxidation Processes for Water Treatment” at ACS Spring conference, Chicago, March 25-29, 2007.
2006 Organizer of Wave21 seminar on “New developments of analytical methods for drinking water analysis”, Dübendorf, Sept. 15, 2006,
2005 Organizer of Wave21 seminar on “New applications of ozone in water treatment”, Sept. 23, 2005, Dübendorf
1999 Co-organizer of 200th Anniversary Symposium in honor of Ch. F. Schönbein - the discoverer of ozone, October 1999, Basel.
1995 Organizer of a symposium in honor of J. Hoigné, June, 1995, Dübendorf, Switzerland
1991 Co-organizer of the workshop "Chemodynamics of Groundwaters", November, 1991, Mont Sainte-Odile, France
Horst Vogel
Horst Vogel est né en 1948 à Würzburg, Allemagne. Après ses études en chimie, il obtient le diplôme de chimie en 1974 de l'Université de Würzburg.Il entreprend ensuite un travail de doctorat au Max-Planck Institut für Biophysikalische Chemie de Göttingen, et obtient en 1978 le grade de docteur ès sciences de l'Université de Göttingen. De 1978 à 1983 il effectue des recherches au Max-Planck Institut für Biologie à Tübingen et en 1984, il rejoint le Biocentre à Bâle où il travaille jusqu'en 1989, effectuant une année au Karolinska Institute à Stockholm. En 1989, Horst Vogel rejoint l'institut de chimie physique de l'EPFL où il dirige un groupe travaillant dans les domaines de la biophysique et de la bioélectronique.
Depuis le 1er octobre 1994 il est profeseur en chimie physique des polymères et membranes au Département de chimie de EPFL. Ses intérêts de recherche sont l'étude de la structure et de la dynamique de récepteurs membranaires et l'auto-assemblage des biomolécules aux interfaces pour développer de nouveaux biocapteurs dans le domaine de micro- et nanotechnologie. Il enseigne les sciences du vivant, la biophysique et biochimie, et des chapitres concernant la biotechnologie.
Dipl. in Chemistry1974-Univ. Würzburg, DE
Ph.D.-1978-MPI für Biophys. Chemie, Göttingen, DE
Maria del Carmen Sandi Perez
ACADEMIC POSITION:
Professor, Director of the Laboratory of Behavioral Genetics, Brain Mind Institute, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland.
EDUCATION:
BS MS Salamanca, Spain, 1984
PhD Cajal Institute, CSIC, and University Autonoma of Madrid, Spain, 1988
PROFESSIONAL EXPERIENCE:
Postdoc at INSERM, Bordeaux, France, and Cajal Institute Madrid, Spain, 1989-1990
Postdoc at the Open University, UK, 1991-1992, 1996
Research Associate, Cajal Institute, CSIC, Madrid, 1993-1995
Associate Professor Tenured, UNED University, Madrid, 1996-2003
Sabbatical Professor, University of Bern, Switzerland, 2002-2003
Assistant Professor Tenure-Track, EPFL, 2003-2007
Associate Professor Tenured, EPFL, 2007-2012
Full Professor, EPFL, 2012-
Director, Brain Mind Institute, EPFL, 2012-
PRINCIPAL BOARDS:
President, European Brain and Behavior Society (EBBS), 2009-2012
Editor-in-Chief Frontiers in Behavioral Neuroscience
Member of Scientific Advisory Panel, European College Neuropsychopharmacology (ECNP)
Member of the European Dana Alliance for the Brain (EDAB)
Associate Editor Frontiers in Neuroscience
Editorial Board Member Neurobiology of Learning and Memory
Editorial Board Member Journal of Psychiatry Research
Editorial Board Member Stress
Editorial Board Member Biology of Mood and Anxiety Disorders
Editorial Board Member Neuroscience and Biobehavioral Reviews
Martinus Gijs
Martin A.M. Gijs received his degree in physics in 1981 from the Katholieke Universiteit Leuven, Belgium and his Ph.D. degree in physics at the same university in 1986. He joined the Philips Research Laboratories in Eindhoven, The Netherlands, in 1987. Subsequently, he has worked there on micro-and nano-fabrication processes of high critical temperature superconducting Josephson and tunnel junctions, the microfabrication of microstructures in magnetic multilayers showing the giant magnetoresistance effect, the design and realisation of miniaturised motors for hard disk applications and the design and realisation of planar transformers for miniaturised power applications. He joined EPFL in 1997. His present interests are in developing technologies for novel magnetic devices, new microfabrication technologies for microsystems fabrication in general and the development and use of microsystems technologies for microfluidic and biomedical applications in particular.