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Many cancer therapeutic agents elicit resistance that renders them ineffective and often produces cross-resistance to other drugs. One of the most common mechanisms of resistance involves P-glycoprotein (Pgp)-mediated drug efflux. To address this problem, ...
The use of green plants specifically chosen or tailored for the remediation of polluted soils and brownfields, the treatment of industrial wastewater or the removal of volatile organic compounds from indoor or outdoor air is becoming essential for sustaina ...
DICER is a central regulator of microRNA maturation. However, little is known about mechanisms regulating its expression in development or disease. While profiling miRNA expression in differentiating melanocytes, two populations were observed: some upregul ...
The amount of data generated by the infra-red and visible cameras at ITER is expected to be considerably larger than most diagnostics. ITER will have 12 infra-red cameras plus 12 visible cameras in four different equatorial port plugs. Each of the ports wi ...
The term "phytotechnologies" refers to the application of science and engineering to provide solutions involving plants, including phytoremediation options using plants and associated microbes to remediate environmental compartments contaminated by trace e ...
The establishment of riparian pioneer vegetation is of crucial importance within river restoration projects. After germination or vegetative reproduction on river bars juvenile plants are often exposed to mortality by uprooting caused by floods. At later s ...
Stimulation of resident cells by NF-kappa B activating cytokines is a central element of inflammatory and degenerative disorders of the central nervous system (CNS). This disease-mediated NF-kappa B activation could be used to drive transgene expression se ...
To find out whether the AGO-miRNA complex is more sensitive to the accessibility of a particular region inside the seed match, we analyze in detail the accessibility of a wide set of miRNA binding sites validated by PAR-CLIP and HITS-CLIP experiments. Our ...
Cold Spring Harbor Lab Press, Publications Dept2012
Background: In European mountains, where semi-natural grasslands have high cultural and nature conservation value, land-use legacies from past ploughing are associated with distinct floristic compositions and ecosystem properties. It remains unknown if the ...
Invasion success is favoured by the introduction of pre-adapted genotypes. In addition, novel pressures in the introduced range may lead to phenotypic changes related to fitness or competitive ability of introduced plants. Polyploidy appears to be over-rep ...