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The Diels-Alder adduct of furan and 1-cyanovinyl (1'R)-camphanate was converted into methyl[(tert-butyl)dimethylsilyl 5-deoxy-2,3-O-isopropylidene-beta-L-ribo-hexofuranosid]uronate ((+)-4). Reduction with diisobutylaluminium hydride gave the corresponding ...
Heritable inactivation of genes occurs in specific chromosomal domains located at the silent mating type loci and at telomeres of S. cerevisiae. The SIR genes (for silent information regulators) are trans-acting factors required for this repression mechani ...