Publications related to Genetically modified animal

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

Patrick Aebischer, Matthias Lütolf, Bernard Schneider, Steffen Cosson, Aurélien Lathuilière

The rapid increase in the number of approved therapeutic proteins, including recombinant antibodies, for diseases necessitating chronic treatments raises the question of the overall costs imposed on healthcare systems. It is therefore important to investig ...

Elsevier2014

Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation

Patrick Aebischer, Bernard Schneider, Marc Moniatte, Aurélien Lathuilière

The controlled delivery of antibodies by immunoisolated bioimplants containing genetically engineered cells is an attractive and safe approach for chronic treatments. To reach therapeutic antibody levels there is a need to generate renewable cell lines, wh ...

Elsevier2014

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

Ozgün Gökce, Davide Franceschini

Protein acetylation, which is central to transcriptional control as well as other cellular processes, is disrupted in Huntington's disease (HD). Treatments that restore global acetylation levels, such as inhibiting histone deacetylases (HDACs), are effecti ...

Oxford University Press2014

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Véronique Michaud, Hans Georg Limberger, Georgios Violakis, Roohollah Sarfaraz Khabbaz

The adhesive bonding of composite materials can be applied to assemble light-weight structures for aeronautical applications. However, the application of adhesive bonds in primary load-bearing structures is limited by the lack of adequate techniques to mon ...

2014

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Véronique Michaud, John Botsis, Hans Georg Limberger, Georgios Violakis, Roohollah Sarfaraz Khabbaz, Luis Pablo Canal Casado

Elsevier2014

Hydrological modelling of the Zambezi River Basin taking into account floodplain behaviour by a modified reservoir approach

Anton Schleiss, Théodora Cohen Liechti, David Ferràs Segura

Floodplains are regions of great interest for environmental assessment as they constitute important ecological reserves and contribute efficiently to natural flood attenuation. However, the implementation of a model describing the basic hydrological behavi ...

2014

Methods to study Drosophila immunity

Bruno Lemaitre, Olivier Binggeli, Andrew Jonathan Bretscher

Innate immune mechanisms are well conserved throughout evolution, and many theoretical concepts, molecular pathways and gene networks are applicable to invertebrate model organisms as much as vertebrate ones. Drosophila immunity research benefits from an e ...

Elsevier2014

Host lifestyle affects human microbiota on daily timescales

Matthew Christopher Blackburn

Background: Disturbance to human microbiota may underlie several pathologies. Yet, we lack a comprehensive understanding of how lifestyle affects the dynamics of human-associated microbial communities. Results: Here, we link over 10,000 longitudinal measur ...

Biomed Central Ltd2014

Overexpression of the tcp Gene Cluster Using the T7 RNA Polymerase/Promoter System and Natural Transformation-Mediated Genetic Engineering of Vibrio cholerae

Melanie Blokesch

The human pathogen and aquatic bacterium Vibrio cholerae belongs to the group of naturally competent bacteria. This developmental program allows the bacterium to take up free DNA from its surrounding followed by a homologous recombination event, which allo ...

Public Library of Science2013

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Genetically modified animal

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Functional analysis of NR2E3 in retinal degenerations

Hydrological modelling of the Zambezi River Basin taking into account floodplain behaviour by a modified reservoir approach

Methods to study Drosophila immunity

Host lifestyle affects human microbiota on daily timescales

Overexpression of the tcp Gene Cluster Using the T7 RNA Polymerase/Promoter System and Natural Transformation-Mediated Genetic Engineering of Vibrio cholerae

Graph Chatbot

Chat with Graph Search

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells

Hydrological modelling of the Zambezi River Basin taking into account floodplain behaviour by a modified reservoir approach

Methods to study Drosophila immunity

Host lifestyle affects human microbiota on daily timescales

Overexpression of the tcp Gene Cluster Using the T7 RNA Polymerase/Promoter System and Natural Transformation-Mediated Genetic Engineering of Vibrio cholerae

Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Monitoring strain gradients in adhesive composite joints by embedded fiber Bragg grating sensors

Functional analysis of NR2E3 in retinal degenerations