Concept

Oxidative phosphorylation

Related publications (383)

Lentiviral Transgenesis as a Tool to Study the Role of Uncoupling Protein Isoforms in the Nervous System

A tight coupling exists between synaptic activity and glucose utilization by astrocytes. Metabolic cooperation between neurons and astrocytes mediates this coupling. During synaptic activation, glutamate that is released in the synaptic cleft as a neurotra ...

EPFL2011

Evolution of algal toxicity during (photo)oxidative degradation of diuron

Urs von Gunten, Kristin Schirmer, Silvio Canonica

In the aquatic environment and in engineered water treatment systems, organic contaminants can undergo oxidative and photochemical transformations. For an overall risk assessment, the toxicity of the resulting transformation products has to be investigated ...

2011

Photocatalytic discoloration of aqueous malachite green solutions by UV-illuminated TiO2 nanoparticles under air and nitrogen atmospheres: effects of counter-ions and pH

César Pulgarin, Christophe Roussel

Under air atmosphere, the photocatalytic discoloration of malachite green (MG) aqueous solutions (a triphenylmethane dye) in the presence of TiO2 and UV light followed an oxidative pathway, involving an N-demethylation process evidenced by a blue shifting ...

2011

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Richardus Houtkooper, Hiroyasu Yamamoto

SIRT1 regulates energy homeostasis by controlling the acetylation status and activity of a number of enzymes and transcriptional regulators. The fact that NAD(+) levels control SIRT1 activity confers a hypothetical basis for the design of new strategies to ...

Elsevier2011

Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T

Rolf Gruetter, Bernard Lanz, João Miguel das Neves Duarte

Cerebral metabolism is compartmentalized between neurons and glia. Although glial glycolysis is thought to largely sustain the energetic requirements of neurotransmission while oxidative metabolism takes place mainly in neurons, this hypothesis is matter o ...

Frontiers Research Foundation2011

PHOTOCATALYTIC DISINFECTION TREATMENTS: VIABILITY, CULTIVABILITY AND METABOLIC CHANGES OF E. coli USING DIFERENT MESUREMENTS METHODS

César Pulgarin, Julien Wist

In this work, the oxidative stress was produced by the illumination of either fixed TiO2 or suspended TiO2. and the relation between cultivability and viability under oxidative conditions was studied using a Direct Viable Count (DVC) and Fluorescence In Si ...

2011

CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability

Johan Auwerx, Carlos Canto Alvarez, Chikage Mataki, Hiroyasu Yamamoto, Lilia Noriega Lopez, Jiujiu Yu

The nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase SIRT1 is a major metabolic regulator activated by energy stresses such as fasting or calorie restriction. SIRT1 activation during fasting not only relies on the increase in the NAD(+)/NAD ...

2011

The metabolic footprint of aging in mice

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Pénélope Andreux, Raphaël Doenlen, Richardus Houtkooper, Ellen Helena Jeninga

Aging is characterized by a general decline in cellular function, which ultimately will affect whole body homeostasis. Although DNA damage and oxidative stress all contribute to aging, metabolic dysfunction is a common hallmark of aging at least in inverte ...

2011

Effect of heterogeneity on enhanced reductive dechlorination: Analysis of remediation efficiency and groundwater acidification

David Andrew Barry, Christof Holliger, Alessandro Brovelli, Clare Robinson, Elsa Marina Lacroix

Enhanced reductive dehalogenation is an attractive in situ treatment technology for chlorinated contaminants. The process includes two acid-forming microbial reactions: fermentation of an organic substrate resulting in short-chain fatty acids, and dehaloge ...

2011

E2F transcription factor-1 regulates oxidative metabolism

Johan Auwerx

Cells respond to stress by coordinating proliferative and metabolic pathways. Starvation restricts cell proliferative (glycolytic) and activates energy productive (oxidative) pathways. Conversely, cell growth and proliferation require increased glycolytic ...

2011

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