Concept

Metabolic disorder

Related publications (93)

Effects of spatiotemporal variations on metabolic control: approximate analysis using (log)linear kinetic models

For many metabolic systems, available exptl. data allow description of the system by elasticities and control coeffs. The availability of information of this kind motivated the development of a (log)linear kinetic model of metabolic systems that is complet ...

1997

MCA has more to say

Vassily Hatzimanikatis

A review with many refs. The recent development of two math. frameworks for the anal. and design of metabolic systems is reviewed here with many refs. Both frameworks employ a (log)linear kinetic metabolic model that is constructed making direct, explicit ...

1996

Analysis and design of metabolic reaction networks via mixed-integer linear optimization

Vassily Hatzimanikatis

Improvements in bioprocess performance can be achieved by genetic modifications of metabolic control structures. A novel optimization problem helps quant. understanding and rational metabolic engineering of metabolic reaction pathways. Maximizing the perfo ...

1996

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